UniProt Accession

 CD9_RAT; P40241 

Genbank Protein ID

 X76489 

Genbank Nucleotide ID

 CAA54027.1 

Protein Name

 CD9 antigen 

Protein Synonyms/Alias

 CD9 

Gene Name

 Cd9 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
129	FYKDTYQKLRNKDEP	acetylation	[1]
133	TYQKLRNKDEPQRET	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion (By similarity). 

Sequence Annotation

 LIPID 9 9 S-palmitoyl cysteine (By similarity).
 LIPID 76 76 S-palmitoyl cysteine (By similarity).
 LIPID 77 77 S-palmitoyl cysteine (By similarity).
 LIPID 85 85 S-palmitoyl cysteine (By similarity).
 LIPID 216 216 S-palmitoyl cysteine (By similarity).
 LIPID 217 217 S-palmitoyl cysteine (By similarity).
 CARBOHYD 50 50 N-linked (GlcNAc...) (Potential).  

Keyword

 Cell adhesion; Complete proteome; Direct protein sequencing; Disulfide bond; Fertilization; Glycoprotein; Lipoprotein; Membrane; Palmitate; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 226 AA 

Protein Sequence

Gene Ontology

 GO:0016324; C:apical plasma membrane; IDA:RGD.
 GO:0009986; C:cell surface; IDA:RGD.
 GO:0009897; C:external side of plasma membrane; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0007420; P:brain development; IEP:RGD.
 GO:0007155; P:cell adhesion; ISS:UniProtKB.
 GO:0006928; P:cellular component movement; ISS:UniProtKB.
 GO:0007342; P:fusion of sperm to egg plasma membrane; ISS:UniProtKB.
 GO:0008285; P:negative regulation of cell proliferation; IEA:Compara.
 GO:0014003; P:oligodendrocyte development; IEP:RGD.
 GO:0030913; P:paranodal junction assembly; ISS:UniProtKB.
 GO:0009414; P:response to water deprivation; IEP:RGD. 

Interpro

 IPR000301; Tetraspanin.
 IPR018499; Tetraspanin/Peripherin.
 IPR018503; Tetraspanin_CS.
 IPR008952; Tetraspanin_EC2. 

Pfam

 PF00335; Tetraspannin 

SMART

  

PROSITE

 PS00421; TM4_1 

PRINTS

 PR00259; TMFOUR.