| Tag | Content |
|---|
| CPLM ID | CPLM-004048 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Cytochrome P450 2B9 |
Protein Synonyms/Alias | CYPIIB9; Cytochrome P450 clone PF26; Cytochrome P450-16-alpha; Testosterone 16-alpha hydroxylase |
Gene Name | Cyp2b9 |
Gene Synonyms/Alias | Cyp2b-9; Rip |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 237 | VHRQIVKKQQELLDY | phosphoglycerylation | [1] |
|
Reference | [1] Functional lysine modification by an intrinsically reactive primary glycolytic metabolite. Moellering RE, Cravatt BF. Science. 2013 Aug 2;341(6145):549-53. [ PMID: 23908237] |
Functional Description | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. |
Sequence Annotation | METAL 436 436 Iron (heme axial ligand) (By similarity).
MOD_RES 128 128 Phosphoserine; by PKA (By similarity). |
Keyword | Complete proteome; Endoplasmic reticulum; Heme; Iron; Membrane; Metal-binding; Microsome; Monooxygenase; Oxidoreductase; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 491 AA |
Protein Sequence | MDPSVLLLLA VLLSLFLLLV RGHAKIHGHL PPGPHPLPLL GNLLQMDRGG LLKCFIQLQE 60
KHGDVFTVHL GPRPVVVLCG TQTIREALVD HAEAFSGRGT IAAAQLVMQD YGIFFASGQR 120
WKTLRRFSLA TMKEFGMGKR SVEERIKEEA QCLVEELKKY QGVPLDPTFL FQCITANIIC 180
SIVFGERFDY TDDQFLHLLN LMYKIFSLLS SFSGQMFELF SGFLKYFPGV HRQIVKKQQE 240
LLDYIAHSVE KHKATLDPSA PRDYIDTYLL RMEKEKSNHN TEFHHQNLMM SVLSLFFVGT 300
ETTSATLHYG VLLMLKYPHV TEKVQKEIDQ VIGSHRLPTL DDRTKMPYTD AVIHEIQRFS 360
DLVPIGLPHK VIKDTLFRGY LLPKNTEVYP VLSSALHDPQ YFEQPDKFNP EQFLDANGAL 420
KKCEAFLPFS TGKRICLGES IARNELFIFF TTILQNFSVA SPVAPKDIDL TPKESGIGKI 480
PPAHQIYFLA R 491 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0070330; F:aromatase activity; IEA:EC. GO:0009055; F:electron carrier activity; IEA:InterPro. GO:0020037; F:heme binding; IEA:InterPro. GO:0005506; F:iron ion binding; IEA:InterPro. GO:0035634; P:response to stilbenoid; IEP:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |