CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027519
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 LP02262p 
Protein Synonyms/Alias
 Lethal (1) G0255, isoform B 
Gene Name
 l(1)G0255 
Gene Synonyms/Alias
 l(1)G0255-RB; CG4094; Dmel_CG4094 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
17SDTFGELKVPADKYYacetylation[1]
22ELKVPADKYYGAQTMacetylation[1]
169NNLKPAIKTLHDALRacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Lyase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 467 AA 
Protein Sequence
MASQEFRVES DTFGELKVPA DKYYGAQTMR SQINFPIGGA TERMPKPVVQ AMGILKKAAA 60
EVNKEFGLDS KVSEAISKAA DDVISGKLYD DHFPLVIWQT GSGTQSNMNV NEVISNRAIE 120
LLGGKLGSKT PVHPNDHVNK SQSSNDTFPT AIHISVALEL NNNLKPAIKT LHDALRAKSE 180
EFKDIIKIGR THTMDAVPLT LGQEFSGYAQ QLAYAQERID ACLPRVYELA LGGTAVGTGL 240
NTRKGFAEKC AAKIAELTSL PFVTAPNKFE ALAARDAMVE VHGVLNTIAV SLMKIANDIR 300
FLGSGPRCGL GELSLPENEP GSSIMPGKVN PTQCESLTML SAQVMGNQVA VTIGGSNGHF 360
ELNVFKPLIV SNVLRSIRLL SDGSRTFTAN CVNGIQANRE NIAKIMNESL MLVTALNPHI 420
GYDKAAKIAK TAHKNGTTLK EEAINLGYLT EQQFNDWVRP EQMLGPK 467 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:FlyBase.
 GO:0045239; C:tricarboxylic acid cycle enzyme complex; IEA:InterPro.
 GO:0004333; F:fumarate hydratase activity; IEA:EC.
 GO:0006106; P:fumarate metabolic process; IEA:InterPro.
 GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro. 
Interpro
 IPR005677; Fum_hydII.
 IPR024083; Fumarase/histidase_N.
 IPR018951; Fumarase_C_C.
 IPR000362; Fumarate_lyase.
 IPR020557; Fumarate_lyase_CS.
 IPR022761; Fumarate_lyase_N.
 IPR008948; L-Aspartase-like. 
Pfam
 PF10415; FumaraseC_C
 PF00206; Lyase_1 
SMART
  
PROSITE
 PS00163; FUMARATE_LYASES 
PRINTS
 PR00149; FUMRATELYASE.