UniProt Accession

 E9PXV4_MOUSE; E9PXV4 

Genbank Protein ID

 AC121301 

Genbank Nucleotide ID

  

Protein Name

 Bile acyl-CoA synthetase 

Protein Synonyms/Alias

  

Gene Name

 Slc27a5 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
159	CQAAWVLKAKLKDAV	acetylation	[1]
159	CQAAWVLKAKLKDAV	ubiquitination	[2]
163	WVLKAKLKDAVIQNT	acetylation	[3]
163	WVLKAKLKDAVIQNT	ubiquitination	[2]
284	ASLRATIKWKSPAIF	acetylation	[1]
302	SGTTGLPKPAILSHE	ubiquitination	[2]
398	VPEQPEDKIHTVRLA	ubiquitination	[2]

Reference

 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 418 AA 

Protein Sequence

Gene Ontology

 GO:0009925; C:basal plasma membrane; IDA:MGI.
 GO:0005783; C:endoplasmic reticulum; TAS:MGI.
 GO:0015245; F:fatty acid transporter activity; IDA:MGI.
 GO:0004467; F:long-chain fatty acid-CoA ligase activity; TAS:MGI.
 GO:0008206; P:bile acid metabolic process; IMP:MGI.
 GO:0046951; P:ketone body biosynthetic process; IMP:MGI.
 GO:0015911; P:plasma membrane long-chain fatty acid transport; IMP:MGI.
 GO:0006642; P:triglyceride mobilization; IMP:MGI. 

Interpro

 IPR020845; AMP-binding_CS.
 IPR000873; AMP-dep_Synth/Lig. 

Pfam

 PF00501; AMP-binding 

SMART

  

PROSITE

 PS00455; AMP_BINDING 

PRINTS