CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024113
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Apolipoprotein M 
Protein Synonyms/Alias
 Apo-M; ApoM 
Gene Name
 Apom 
Gene Synonyms/Alias
 Ng20 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
108TYRLTEGKGNMELRTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid (By similarity). 
Sequence Annotation
 BINDING 138 138 Fatty acid (By similarity).
 BINDING 145 145 Fatty acid (By similarity).
 DISULFID 23 169 By similarity.
 DISULFID 95 185
 DISULFID 130 159  
Keyword
 3D-structure; Complete proteome; Disulfide bond; HDL; Lipid transport; Reference proteome; Secreted; Signal; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 190 AA 
Protein Sequence
MFHQVWAALL SLYGLLFNSM NQCPEHSQLT ALGMDDTETP EPHLGLWYFI AGAASTTEEL 60
ATFDPVDNIV FNMAAGSAPR QLQLRATIRT KSGVCVPRKW TYRLTEGKGN MELRTEGRPD 120
MKTDLFSSSC PGGIMLKETG QGYQRFLLYN RSPHPPEKCV EEFQSLTSCL DFKAFLVTPR 180
NQEACPLSSK 190 
Gene Ontology
 GO:0034365; C:discoidal high-density lipoprotein particle; IDA:BHF-UCL.
 GO:0034362; C:low-density lipoprotein particle; IEA:Compara.
 GO:0034366; C:spherical high-density lipoprotein particle; IEA:Compara.
 GO:0034361; C:very-low-density lipoprotein particle; IEA:Compara.
 GO:0016209; F:antioxidant activity; IDA:BHF-UCL.
 GO:0005319; F:lipid transporter activity; IEA:Compara.
 GO:0005543; F:phospholipid binding; ISS:BHF-UCL.
 GO:0033344; P:cholesterol efflux; IMP:BHF-UCL.
 GO:0034380; P:high-density lipoprotein particle assembly; IMP:BHF-UCL.
 GO:0034384; P:high-density lipoprotein particle clearance; IMP:BHF-UCL.
 GO:0034375; P:high-density lipoprotein particle remodeling; IMP:BHF-UCL.
 GO:0042157; P:lipoprotein metabolic process; IMP:MGI.
 GO:0034445; P:negative regulation of plasma lipoprotein particle oxidation; IDA:BHF-UCL.
 GO:0009749; P:response to glucose stimulus; IEA:Compara.
 GO:0043691; P:reverse cholesterol transport; IMP:MGI. 
Interpro
 IPR022734; ApoM.
 IPR012674; Calycin.
 IPR011038; Calycin-like. 
Pfam
 PF11032; ApoM 
SMART
  
PROSITE
  
PRINTS