CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001836
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 D-serine dehydratase 
Protein Synonyms/Alias
 D-serine deaminase; DSD 
Gene Name
 dsdA 
Gene Synonyms/Alias
 b2366; JW2363 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
17IAQYPLVKDLVALKEacetylation[1]
93AMQKRLEKEYQQPISacetylation[1]
440EMNQYLAKGR*****acetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 MOD_RES 118 118 N6-(pyridoxal phosphate)lysine.  
Keyword
 3D-structure; Complete proteome; Direct protein sequencing; Lyase; Pyridoxal phosphate; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 442 AA 
Protein Sequence
MENAKMNSLI AQYPLVKDLV ALKETTWFNP GTTSLAEGLP YVGLTEQDVQ DAHARLSRFA 60
PYLAKAFPET AATGGIIESE LVAIPAMQKR LEKEYQQPIS GQLLLKKDSH LPISGSIKAR 120
GGIYEVLAHA EKLALEAGLL TLDDDYSKLL SPEFKQFFSQ YSIAVGSTGN LGLSIGIMSA 180
RIGFKVTVHM SADARAWKKA KLRSHGVTVV EYEQDYGVAV EEGRKAAQSD PNCFFIDDEN 240
SRTLFLGYSV AGQRLKAQFA QQGRIVDADN PLFVYLPCGV GGGPGGVAFG LKLAFGDHVH 300
CFFAEPTHSP CMLLGVHTGL HDQISVQDIG IDNLTAADGL AVGRASGFVG RAMERLLDGF 360
YTLSDQTMYD MLGWLAQEEG IRLEPSALAG MAGPQRVCAS VSYQQMHGFS AEQLRNTTHL 420
VWATGGGMVP EEEMNQYLAK GR 442 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:EcoliWiki.
 GO:0008721; F:D-serine ammonia-lyase activity; IDA:EcoCyc.
 GO:0016836; F:hydro-lyase activity; IDA:EcoliWiki.
 GO:0030170; F:pyridoxal phosphate binding; IDA:EcoCyc.
 GO:0036088; P:D-serine catabolic process; IDA:EcoCyc.
 GO:0051410; P:detoxification of nitrogen compound; IMP:EcoCyc.
 GO:0006974; P:response to DNA damage stimulus; IEP:EcoliWiki. 
Interpro
 IPR011780; D_Ser_am_lyase.
 IPR000634; Ser/Thr_deHydtase_PyrdxlP-BS.
 IPR001926; Trp_syn_b_sub_like_PLP_eny_SF. 
Pfam
 PF00291; PALP 
SMART
  
PROSITE
 PS00165; DEHYDRATASE_SER_THR 
PRINTS