| Tag | Content |
|---|
| CPLM ID | CPLM-007858 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Trafficking protein particle complex III-specific subunit 85 |
Protein Synonyms/Alias | TRAPP III-specific subunit 85; Muddled meiosis protein 1; Sporulation protein GSG1; Transport protein particle 85 kDa subunit |
Gene Name | TRS85 |
Gene Synonyms/Alias | GSG1; MUM1; YDR108W; YD9727.04 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 502 | RIQRGKGKESNSLDV | ubiquitination | [1] | | 687 | SAPRPSEKNLTRTSV | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Specific subunit of the TRAPP III complex that acts as an autophagy-specific guanine nucleotide exchange factor (GEF) for YPT1. TRS85 directs the TRAPP III complex to the phagophore assembly site (PAS) that is involved in autophagosome formation. Required for membrane expansion during autophagy and the CVT pathway. Required for sporulation. Has a role late in meiosis following DNA replication. |
Sequence Annotation | |
Keyword | Autophagy; Complete proteome; Meiosis; Reference proteome; Sporulation; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 698 AA |
Protein Sequence | MVFSYEHYMN LLFHLDNSKE TVPPEIAKRI ISNAIAPVIT VTSTPLFDKH IQETYKVDSL 60
YMLLRFFGGC VSDRDQANEA KVGQHEHEVC DASDSTDSIP KNKNLEVPNL SKKGSRSRSN 120
SLFQRDSTQS QYIRFTRPLG DLIETRDAND MLFNYHSLEV FLDNYLKLVA ANTDEMVPHN 180
LLKKSIYHSF FSLAISSTNN LSPYETFNHP ILSLIALDIS NGEVYEDARD LLVNFKNLNH 240
NTENFPIFMN TNEMLPVFLL CYNDDSQEEF EKCQALAKKL KKQLFVESIL LALWKDSFIY 300
DENSVIQLHQ PVMSSLEEIL FFLQAPTQTT LSLALINSIY DMLDYLVYDL MIPFMKRKVS 360
FWEETILQPR KSLFNGAKFF KKFMNKNPVN GNHQHNSLTR DSQGNEYFAS SSSEFLMRKL 420
ADWSMMLSDF KTAYSTYESL MDDLDAFPKY LASCIEWCAV SLLMGAQSIV TVKMIKNDIN 480
PLIERALATY ENCSRIQRGK GKESNSLDVT EPVRSYETRC MILASELFLS LSNTWTSTPY 540
AIQYLETILD ECKLGPCSQI MVWERLSDCY NLRVDPRIKH RVGAMKKDAK DTEDLRGEHK 600
YSTDHFTDED ILSEGLTRRR KAAFFRLIAA KKWAEQKQWR QVSWCLKDIE STYSEIKFLH 660
GNGLILSKLK NQLNLKDVDS APRPSEKNLT RTSVSFIG 698 |
Gene Ontology | GO:0000407; C:pre-autophagosomal structure; IDA:SGD. GO:0030008; C:TRAPP complex; IDA:SGD. GO:0032258; P:CVT pathway; IMP:SGD. GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD. GO:0016236; P:macroautophagy; IMP:SGD. GO:0007126; P:meiosis; IMP:SGD. GO:0030242; P:peroxisome degradation; IMP:SGD. GO:0034727; P:piecemeal microautophagy of nucleus; IMP:SGD. GO:0034497; P:protein localization to pre-autophagosomal structure; IMP:SGD. GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. GO:0016050; P:vesicle organization; IMP:SGD. |
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PRINTS | |