CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013382
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 FLYWCH-type zinc finger-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 FLYWCH1 
Gene Synonyms/Alias
 KIAA1552 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
146VGDKVYWKCRQHAELubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
 ZN_FING 116 174 FLYWCH-type 1.
 ZN_FING 273 331 FLYWCH-type 2.
 ZN_FING 421 479 FLYWCH-type 3.
 ZN_FING 509 567 FLYWCH-type 4.
 ZN_FING 600 658 FLYWCH-type 5.
 MOD_RES 21 21 Phosphoserine.
 MOD_RES 261 261 Phosphoserine.
 MOD_RES 503 503 Phosphoserine.
 MOD_RES 591 591 Phosphoserine.
 MOD_RES 696 696 Phosphoserine.  
Keyword
 3D-structure; Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 716 AA 
Protein Sequence
MPLPEPSEQE GESVKAGQEP SPKPGTDVIP AAPRKPREFS KLVLLTASDQ DEDGVGSKPQ 60
EVHCVLSLEM AGPATLASTL QILPVEEQGG VVQPALEMPE QKCSKLDAAA PQSLEFLRTP 120
FGGRLLVLES FLYKQEKAVG DKVYWKCRQH AELGCRGRAI TRGLRATVMR GHCHAPDEQG 180
LEARRQREKL PSLALPEGLG EPQGPEGPGG RVEEPLEGVG PWQCPEEPEP TPGLVLSKPA 240
LEEEEAPRAL SLLSLPPKKR SILGLGQARP LEFLRTCYGG SFLVHESFLY KREKAVGDKV 300
YWTCRDHALH GCRSRAITQG QRVTVMRGHC HQPDMEGLEA RRQQEKAVET LQAGQDGPGS 360
QVDTLLRGVD SLLYRRGPGP LTLTRPRPRK RAKVEDQELP TQPEAPDEHQ DMDADPGGPE 420
FLKTPLGGSF LVYESFLYRR EKAAGEKVYW TCRDQARMGC RSRAITQGRR VTVMRGHCHP 480
PDLGGLEALR QREKRPNTAQ RGSPGGPEFL KTPLGGSFLV YESFLYRREK AAGEKVYWTC 540
RDQARMGCRS RAITQGRRVM VMRRHCHPPD LGGLEALRQR EHFPNLAQWD SPDPLRPLEF 600
LRTSLGGRFL VHESFLYRKE KAAGEKVYWM CRDQARLGCR SRAITQGHRI MVMRSHCHQP 660
DLAGLEALRQ RERLPTTAQQ EDPEKIQVQL CFKTCSPESQ QIYGDIKDVR LDGESQ 716 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 
Interpro
 IPR007588; Znf_FLYWCH. 
Pfam
 PF04500; FLYWCH 
SMART
  
PROSITE
  
PRINTS