UniProt Accession

 B7Z509_HUMAN; B7Z509 

Genbank Protein ID

 AC005540; AC067945; AC079162; AK298266 

Genbank Nucleotide ID

 BAH12745.1 

Protein Name

 Glutaminase kidney isoform, mitochondrial 

Protein Synonyms/Alias

 cDNA FLJ55236, highly similar to Glutaminase kidney isoform, mitochondrial (EC 3.5.1.2) 

Gene Name

 GLS 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
44	NLRHFAKKLDPRREG	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 ANK repeat; Complete proteome; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 174 AA 

Protein Sequence

Gene Ontology

 GO:0004359; F:glutaminase activity; IEA:Compara.
 GO:0007610; P:behavior; IEA:Compara.
 GO:0006537; P:glutamate biosynthetic process; IEA:Compara.
 GO:0006543; P:glutamine catabolic process; IEA:Compara.
 GO:0002087; P:regulation of respiratory gaseous exchange by neurological system process; IEA:Compara.
 GO:0007268; P:synaptic transmission; IEA:Compara. 

Interpro

 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR012338; Beta-lactam/transpept-like.
 IPR015868; Glutaminase. 

Pfam

 PF12796; Ank_2
 PF04960; Glutaminase 

SMART

 SM00248; ANK 

PROSITE

 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT 

PRINTS