| Tag | Content |
|---|
| CPLM ID | CPLM-008463 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DNA polymerase I, thermostable |
Protein Synonyms/Alias | Tth polymerase 1 |
Gene Name | polA |
Gene Synonyms/Alias | TTHA1054 |
Created Date | July 27, 2013 |
Organism | Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) |
NCBI Taxa ID | 300852 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 437 | WLYHEVEKPLSRVLA | acetylation | [1] |
|
Reference | [1] Acetylome with structural mapping reveals the significance of lysine acetylation in Thermus thermophilus. Okanishi H, Kim K, Masui R, Kuramitsu S. J Proteome Res. 2013 Aug 1;. [ PMID: 23901841] |
Functional Description | |
Sequence Annotation | REGION 412 834 Polymerase (By similarity). |
Keyword | Complete proteome; DNA damage; DNA repair; DNA replication; DNA-binding; DNA-directed DNA polymerase; Nucleotidyltransferase; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 834 AA |
Protein Sequence | MEAMLPLFEP KGRVLLVDGH HLAYRTFFAL KGLTTSRGEP VQAVYGFAKS LLKALKEDGY 60
KAVFVVFDAK APSFRHEAYE AYKAGRAPTP EDFPRQLALI KELVDLLGFT RLEVPGYEAD 120
DVLATLAKKA EKEGYEVRIL TADRDLYQLV SDRVAVLHPE GHLITPEWLW EKYGLRPEQW 180
VDFRALVGDP SDNLPGVKGI GEKTALKLLK EWGSLENLLK NLDRVKPENV REKIKAHLED 240
LRLSLELSRV RTDLPLEVDL AQGREPDREG LRAFLERLEF GSLLHEFGLL EAPAPLEEAP 300
WPPPEGAFVG FVLSRPEPMW AELKALAACR DGRVHRAADP LAGLKDLKEV RGLLAKDLAV 360
LASREGLDLV PGDDPMLLAY LLDPSNTTPE GVARRYGGEW TEDAAHRALL SERLHRNLLK 420
RLEGEEKLLW LYHEVEKPLS RVLAHMEATG VRLDVAYLQA LSLELAEEIR RLEEEVFRLA 480
GHPFNLNSRD QLERVLFDEL RLPALGKTQK TGKRSTSAAV LEALREAHPI VEKILQHREL 540
TKLKNTYVDP LPSLVHPRTG RLHTRFNQTA TATGRLSSSD PNLQNIPVRT PLGQRIRRAF 600
VAEAGWALVA LDYSQIELRV LAHLSGDENL IRVFQEGKDI HTQTASWMFG VPPEAVDPLM 660
RRAAKTVNFG VLYGMSAHRL SQELAIPYEE AVAFIERYFQ SFPKVRAWIE KTLEEGRKRG 720
YVETLFGRRR YVPDLNARVK SVREAAERMA FNMPVQGTAA DLMKLAMVKL FPRLREMGAR 780
MLLQVHDELL LEAPQARAEE VAALAKEAME KAYPLAVPLE VEVGMGEDWL SAKG 834 |
Gene Ontology | GO:0008409; F:5'-3' exonuclease activity; IEA:InterPro. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW. GO:0001882; F:nucleoside binding; IEA:InterPro. GO:0006281; P:DNA repair; IEA:UniProtKB-KW. GO:0006260; P:DNA replication; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |