| Tag | Content |
|---|
| CPLM ID | CPLM-021139 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Acidic leucine-rich nuclear phosphoprotein 32 family member B |
Protein Synonyms/Alias | Proliferation-related acidic leucine-rich protein PAL31 |
Gene Name | Anp32b |
Gene Synonyms/Alias | Pal31 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 101 | NLSGNNLKDISTLEP | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome (By similarity). |
Sequence Annotation | REPEAT 18 38 LRR 1.
REPEAT 43 64 LRR 2.
REPEAT 65 87 LRR 3.
REPEAT 89 110 LRR 4.
DOMAIN 123 161 LRRCT.
MOD_RES 265 265 Phosphothreonine. |
Keyword | Alternative splicing; Chaperone; Complete proteome; Leucine-rich repeat; Nucleus; Phosphoprotein; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 272 AA |
Protein Sequence | MDMKRRIHLE LRNRTPAAVR ELVLDNCKAM DGKIEGLTDE FVNLEFLSLI SVGLFSVSDL 60
PKLPKLKKLE LSENRIFGGL DRLAEELPSL THLNLSGNNL KDISTLEPLK RLDCLKSLDL 120
FGCEVTNRSD YRETVFRLLP QLSYLDGYDR EDQEAPDSDV EVDSVEEAPD SDGEVDGVDK 180
EEEDEEGEDE EEEEDEDGEE EEDEDEEDED EDEDVEGEDD EDEVSGEVNT TVFFPICVKT 240
KEEEFGHDGE VDEDEEDEDE DEDEEEEESG KGEKRKRETD DEEEEPKNSS RDIPPSSVSP 300
LVIHHQAWGL RPNKIVNVVR FSCKTLAVS 329 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |