CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010497
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Single-stranded DNA-binding protein 2 
Protein Synonyms/Alias
 Sequence-specific single-stranded-DNA-binding protein 2 
Gene Name
 SSBP2 
Gene Synonyms/Alias
 SSDP2 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
4****MYGKGKSNSSAubiquitination[1]
6**MYGKGKSNSSAVPubiquitination[1, 2]
21SDSQAREKLALYVYEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
 DOMAIN 18 50 LisH.
 MOD_RES 321 321 Phosphoserine.
 MOD_RES 333 333 Phosphothreonine.  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 361 AA 
Protein Sequence
MYGKGKSNSS AVPSDSQARE KLALYVYEYL LHVGAQKSAQ TFLSEIRWEK NITLGEPPGF 60
LHSWWCVFWD LYCAAPERRE TCEHSSEAKA FHDYSAAAAP SPVLGNIPPG DGMPVGPVPP 120
GFFQPFMSPR YPGGPRPPLR IPNQALGGVP GSQPLLPSGM DPTRQQGHPN MGGPMQRMTP 180
PRGMVPLGPQ NYGGAMRPPL NALGGPGMPG MNMGPGGGRP WPNPTNANSI PYSSASPGNY 240
VGPPGGGGPP GTPIMPSPAD STNSGDNMYT LMNAVPPGPN RPNFPMGPGS DGPMGGLGGM 300
ESHHMNGSLG SGDMDSISKN SPNNMSLSNQ PGTPRDDGEM GGNFLNPFQS ESYSPSMTMS 360
V 361 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:LIFEdb.
 GO:0005634; C:nucleus; NAS:UniProtKB.
 GO:0003697; F:single-stranded DNA binding; NAS:UniProtKB.
 GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB. 
Interpro
 IPR006594; LisH_dimerisation.
 IPR008116; SSDP_DNA-bd.
 IPR007591; SSDP_ss-bd. 
Pfam
 PF04503; SSDP 
SMART
 SM00667; LisH 
PROSITE
 PS50896; LISH 
PRINTS
 PR01743; SSDNABINDING.