CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024265
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative short-chain type dehydrogenase/reductase MSMEG_6031/MSMEI_5872 
Protein Synonyms/Alias
  
Gene Name
 MSMEG_6031, MSMEI_5872 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
NCBI Taxa ID
 246196 
Lysine Modification
Position
Peptide
Type
References
65AETVELVKGLNRRIVpupylation[1]
Reference
 [1] Expansion of the mycobacterial "PUPylome".
 Watrous J, Burns K, Liu WT, Patel A, Hook V, Bafna V, Barry CE 3rd, Bark S, Dorrestein PC.
 Mol Biosyst. 2010 Feb;6(2):376-85. [PMID: 20094657] 
Functional Description
  
Sequence Annotation
 NP_BIND 11 33 NAD or NADP (By similarity).
 ACT_SITE 171 171 Proton acceptor (By similarity).
 BINDING 158 158 Substrate (By similarity).
 CROSSLNK 65 65 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 Complete proteome; Isopeptide bond; NAD; Oxidoreductase; Reference proteome; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 279 AA 
Protein Sequence
MAGRVEGKVA FITGAARGQG RSHAVRLAEE GADIIAVDVC RRISSNEDIP ASTPEDLAET 60
VELVKGLNRR IVAEEVDVRD YDALKAVVDS GVEQLGGLDI VVANAGIGNG GATLDKTSEA 120
DWDDMIGVNL SGVWKTVKAA VPHLISGGNG GSIILTSSVG GLKAYPHTGH YIAAKHGVVG 180
LMRTFAVELG QHSIRVNSVH PTNVNTPLFM NEGTMKLFRP DLENPGPDDM AVVAQMMHVL 240
PVGWVEPRDI SNAVLFLASD EARYVTGLPM TVDAGSMLK 279 
Gene Ontology
 GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. 
Interpro
 IPR023985; Carveol_DH.
 IPR002198; DH_sc/Rdtase_SDR.
 IPR002347; Glc/ribitol_DH.
 IPR016040; NAD(P)-bd_dom. 
Pfam
 PF00106; adh_short 
SMART
  
PROSITE
 PS00061; ADH_SHORT 
PRINTS
 PR00081; GDHRDH.
 PR00080; SDRFAMILY.