CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038482
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Kif23 
Protein Synonyms/Alias
  
Gene Name
 Kif23 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
544KENYVQEKLNEREKVacetylation[1, 2]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [2] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Microtubule; Motor protein; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 953 AA 
Protein Sequence
MKSAKAKTVR KPVIKKGSQT NLKDPVGVYC RVRPLSFPDQ ECCVEVINST TLQLHTPEGY 60
RLNRNGDYKE TQYSFKRVFG THTTQKELFD VVANPLVDDL IHGKNGLLFT YGVTGSGKTY 120
TMTGSPGSGG LLPRCLNMIF NSIGSFQAKR YVFKSNDRNS MEIQCEVDAL LERQKREALP 180
IPKTPSSKRQ ADPEFADMIN VQEFCKAEEV DEDSVYGVFV SYIEIYNNYI YDLLEEVQFD 240
PIKPKLPQSK TLREDKNHNM YVAGCTEVEV KSTEEAFEVF WRGQKKRRIA NTHLNRESSR 300
SHSVFSIKLV QAPLDADGDN VLQEKEQITI SQLSLVDLAG SERTNRTKAE GNRLREAGNI 360
NQSLMTLRTC MEVLRENQTY GTNKMVPYRD SKLTHLFKNY FDGEGKVRMI VCVNPKAEDY 420
EESLQVMRFA EVTQEVEVAR PVDKVICGLT PGRRYRNLPR GGPVGDEPLV PEVILQSFPP 480
LPPCKLLDIN DEETLPKLAD TLEKRHHLRQ LMTEDLNKKC LAFKALLKEF DNSLSNKENY 540
VQEKLNEREK VISGQKLEIE RLEKKNKTLE YKIEILEKTT TIYEEDKRNL QQELESQNQK 600
LQRQFSDKRR LEARLQGMVT ETSMKWQKEC ERRVAATQLE MQNKLWVKDE KLKQLKAIVT 660
EPKPEKPERP SRERDREKII PRSVSPSPLP LSSNNIAQIS NGQQLMSQPQ LHRRSNSCSS 720
ISVASCISEW EQKLSPFSTP VNVTSLARHR QQEPGQSKTC IVSDRRRGMC WTEGREMVPT 780
FSSEIGVEED HCRRNTPIPV RHRRSRSAGS RWVDHKPASN VQTETVMQPH VPHAITVSVA 840
NEKALAKCEK YMLTHQELAS DGEIQTKVIK GDVYKTRGGG QSVQFTDIET LKQELPTGSR 900
KRRSSTLAPA QPDGTESEWT DVETRCSVAV EMRAGSQLGP GYQHHAQPKR KKP 953 
Gene Ontology
 GO:0097149; C:centralspindlin complex; IEA:Compara.
 GO:0005813; C:centrosome; IEA:Compara.
 GO:0045171; C:intercellular bridge; IDA:MGI.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IEA:InterPro.
 GO:0030496; C:midbody; IEA:Compara.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0007018; P:microtubule-based movement; IEA:InterPro.
 GO:0051256; P:spindle midzone assembly involved in mitosis; IEA:Compara. 
Interpro
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00225; Kinesin 
SMART
 SM00129; KISc 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2 
PRINTS
 PR00380; KINESINHEAVY.