CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031575
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Heat shock 70 kDa protein 4L 
Protein Synonyms/Alias
 Heat shock 70kDa protein 4-like (Predicted), isoform CRA_b; Hspa4l protein 
Gene Name
 Hspa4l 
Gene Synonyms/Alias
 Hspa4l_predicted; rCG_41537 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
68RNTIHGFKKLHGRSFacetylation[1]
93RLPYELQKMPNGSAGacetylation[1]
194DLPSLDEKPRNVVFIacetylation[1]
272RLYQECEKLKKLMSAacetylation[1]
430NHPAPFSKVITFHKKacetylation[1]
436SKVITFHKKEPFELEacetylation[1]
612GKMIMQDKLEKERNDacetylation[1]
634YVYDFRDKLGTVYEKubiquitination[2]
641KLGTVYEKFITPEDMacetylation[1]
641KLGTVYEKFITPEDMubiquitination[2]
677PKQVYVDKLQELKKYacetylation[1]
707KALNDLGKKIQLVLKacetylation[1]
736LDPAEMEKVEKYISDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome; Stress response. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 838 AA 
Protein Sequence
MSVVGIDLGF LNCYIAVARS GGIETIANEY SDRCTPACIS LGSRTRAIGN AAKSQIVTNV 60
RNTIHGFKKL HGRSFDDPIV QTERIRLPYE LQKMPNGSAG VKVRYLEEER PFAIEQVTGM 120
LLAKLKETSE NALKKPVADC VISIPSFFTD AERRSVMAAA QVAGLNCLRL MNETTAVALA 180
YGIYKQDLPS LDEKPRNVVF IDMGHSAYQV SVCAFNKGKL KVLATTFDPY LGGRNFDEAL 240
VDYFCDEFKA KYKINVKENS RALLRLYQEC EKLKKLMSAN ASDLPLNIEC FMNDLDVSSK 300
MNRAQFEQLC ASLLARVEPP LKAVMDQANL QREDINSIEI VGGATRIPAV KEQVTRFFLK 360
DISTTLNADE AVARGCALQC AILSPAFKVR EFSITDLVPY SVTLSWKTSF EEGTGECEVF 420
SKNHPAPFSK VITFHKKEPF ELEAFYTNLH EVPYPDPRIG NFTIQNVFPQ SDGDSSKVKV 480
KVRINIHGIF SVASASVIEK QNLEGDHNDA PMETEASKNE GKEDVDKMQV DQEEGGHQKC 540
HAEHTPEEEI DHTGAKAKAP PSDKQDRINQ TIKKGKIKSI DLPIQSSLYR QLTQDLLNSY 600
IENEGKMIMQ DKLEKERNDA KNAVEEYVYD FRDKLGTVYE KFITPEDMNK LSAMLEDTEN 660
WLYEEGEDQP KQVYVDKLQE LKKYGQPIQM KYVEHEERPK ALNDLGKKIQ LVLKVIEAHR 720
NKDERYDHLD PAEMEKVEKY ISDSMNWLNS KMNAQNKLSL TQDPVVKVSE IVTKSKELDN 780
FCNPIVYKPK PKVEAPEDKT KASSEHNGPM DGQNGAESSP DPPKGGSQHT DSGEMEVD 838 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW. 
Interpro
 IPR018181; Heat_shock_70_CS.
 IPR013126; Hsp_70_fam. 
Pfam
 PF00012; HSP70 
SMART
  
PROSITE
 PS00329; HSP70_2
 PS01036; HSP70_3 
PRINTS
 PR00301; HEATSHOCK70.