CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015340
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc transporter 9 
Protein Synonyms/Alias
 ZnT-9; Human embryonic lung protein; HuEL; Solute carrier family 30 member 9 
Gene Name
 SLC30A9 
Gene Synonyms/Alias
 C4orf1; HUEL 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
223RDFLGNTKPRSRTASubiquitination[1]
479VRAIHDVKATDLGLGubiquitination[1]
487ATDLGLGKVRFKAEVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Plays a role in the p160 coactivator signaling pathway that mediates transcriptional activation by nuclear receptors (By similarity). Plays a role in transcriptional activation of Wnt- responsive genes (By similarity). 
Sequence Annotation
 MOTIF 462 466 LXXLL motif.  
Keyword
 3D-structure; Complete proteome; Ion transport; Membrane; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation; Transmembrane; Transmembrane helix; Transport; Zinc; Zinc transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 568 AA 
Protein Sequence
MLPGLAAAAA HRCSWSSLCR LRLRCRAAAC NPSDRQEWQN LVTFGSFSNM VPCSHPYIGT 60
LSQVKLYSTN VQKEGQGSQT LRVEKVPSFE TAEGIGTELK APLKQEPLQV RVKAVLKKRE 120
YGSKYTQNNF ITGVRAINEF CLKSSDLEQL RKIRRRSPHE DTESFTVYLR SDVEAKSLEV 180
WGSPEALARE KKLRKEAEIE YRERLFRNQK ILREYRDFLG NTKPRSRTAS VFFKGPGKVV 240
MVAICINGLN CFFKFLAWIY TGSASMFSEA IHSLSDTCNQ GLLALGISKS VQTPDPSHPY 300
GFSNMRYISS LISGVGIFMM GAGLSWYHGV MGLLHPQPIE SLLWAYCILA GSLVSEGATL 360
LVAVNELRRN ARAKGMSFYK YVMESRDPST NVILLEDTAA VLGVIIAATC MGLTSITGNP 420
LYDSLGSLGV GTLLGMVSAF LIYTNTEALL GRSIQPEQVQ RLTELLENDP SVRAIHDVKA 480
TDLGLGKVRF KAEVDFDGRV VTRSYLEKQD FDQMLQEIQE VKTPEELETF MLKHGENIID 540
TLGAEVDRLE KELKKRNPEV RHVDLEIL 568 
Gene Ontology
 GO:0005856; C:cytoskeleton; IDA:UniProtKB.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0008324; F:cation transmembrane transporter activity; IEA:InterPro.
 GO:0003682; F:chromatin binding; IEA:Compara.
 GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IEA:Compara.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
 GO:0006289; P:nucleotide-excision repair; TAS:BHF-UCL.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006829; P:zinc ion transport; IEA:UniProtKB-KW. 
Interpro
 IPR002524; Cation_efflux.
 IPR027469; Cation_efflux_TMD.
 IPR009061; DNA-bd_dom_put.
 IPR022656; XPA_C. 
Pfam
 PF01545; Cation_efflux 
SMART
  
PROSITE
  
PRINTS