| Tag | Content |
|---|
| CPLM ID | CPLM-016819 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Sorting nexin-8 |
Protein Synonyms/Alias | |
Gene Name | Snx8 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 196 | GDEFMNCKLAARAKD | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May be involved in several stages of intracellular trafficking. May play a role in intracellular protein transport from early endosomes to the trans-Golgi network (By similarity). |
Sequence Annotation | DOMAIN 68 176 PX.
BINDING 104 104 Phosphatidylinositol 3-phosphate (By
BINDING 130 130 Phosphatidylinositol 3-phosphate (By
BINDING 143 143 Phosphatidylinositol 3-phosphate (By
MOD_RES 446 446 Phosphothreonine (By similarity).
MOD_RES 450 450 Phosphoserine (By similarity). |
Keyword | Complete proteome; Endosome; Lipid-binding; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 459 AA |
Protein Sequence | MTGRAMDPLP SPAVAAAAEA EADEEADPPA TGPRTSQVTE WRALDPGRMQ MPQGNPLLLS 60
YTLQELLAKD TVQVELIPEK KGLFLKHVEY EVSSQRFKSS VYRRYNDFVV FHEVLLHKFP 120
YRMVPALPPK RVLGADREFI EGRRRALKRF INLVARHPPF SEDVLLKLFL SFSGSDVQHK 180
LKEAAQCVGD EFMNCKLAAR AKDFLPADIQ TQFAMSRELI RNVYNSFYKL RDRAERIASR 240
AIDNAADLLI FGKELSALGS DTTPLPSWAA LHLSTWGSLK QALKGLSVEF ALLADRAAQQ 300
GKKEENDVVE KLNLFLDLLQ SYKDLCERHE KGVLHKHQRA LHKYGLMKRQ MMSAAHGREP 360
ESVEQLESRI VEQENVIQTM ELRNYFSLYC LHQETQLVHV YLPLTSHILG AFVNSQIQGH 420
KEMSKVWNDL KPKLSCLFAG PHSVLTPPRS PQEDGVCPH 459 |
Gene Ontology | GO:0031901; C:early endosome membrane; ISS:UniProtKB. GO:0030904; C:retromer complex; IEA:Compara. GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB. GO:0007154; P:cell communication; IEA:InterPro. GO:0034498; P:early endosome to Golgi transport; ISS:UniProtKB. GO:0006886; P:intracellular protein transport; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |