UniProt Accession

 C9JK03_HUMAN; C9JK03 

Genbank Protein ID

 AC024243; AC069200; AC110372 

Genbank Nucleotide ID

  

Protein Name

 Circadian locomoter output cycles protein kaput 

Protein Synonyms/Alias

  

Gene Name

 CLOCK 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
85	IDFLRKHKEITAQSD	ubiquitination	[1]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 182 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005667; C:transcription factor complex; IEA:Compara.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0001190; F:RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription; IEA:Compara.
 GO:0004871; F:signal transducer activity; IEA:InterPro.
 GO:0032922; P:circadian regulation of gene expression; IEA:Compara. 

Interpro

 IPR011598; bHLH_dom.
 IPR001067; Nuc_translocat.
 IPR000014; PAS.
 IPR013767; PAS_fold. 

Pfam

 PF00010; HLH
 PF00989; PAS 

SMART

 SM00353; HLH
 SM00091; PAS 

PROSITE

 PS50888; BHLH
 PS50112; PAS 

PRINTS

 PR00785; NCTRNSLOCATR.