CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-008802
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Actin-related protein 5 
Protein Synonyms/Alias
 Actin-like protein ARP5 
Gene Name
 ARP5 
Gene Synonyms/Alias
 YNL059C; N2430; YNL2430C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
12DASLTPLKAVVIDDPubiquitination[1, 2]
323RMEKLVQKQEEFEYFubiquitination[2]
361FDDERDFKKYLHSLEacetylation[3]
498QVSQNRMKNLASLAEacetylation[3]
Reference
 [1] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [3] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. 
Sequence Annotation
 MOD_RES 7 7 Phosphoserine.
 MOD_RES 24 24 Phosphothreonine.
 MOD_RES 383 383 Phosphoserine.  
Keyword
 Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 755 AA 
Protein Sequence
MSSRDASLTP LKAVVIDDPP LRQTPEPFDE QSAYNPQSPI AIDFGSSKLR AGFVNHATPT 60
HIFPNALTKF RDRKLNKNFT FVGNDTLLDQ AVRSQSRSPF DGPFVTNWNL TEEILDYTFH 120
HLGVVPDNGI PNPILLTERL ATVQSQRTNW YQILFETYNV PGVTFGIDSL FSFYNYNPSG 180
NKTGLVISCG HEDTNVIPVV DGAGILTDAK RINWGGHQAV DYLNDLMALK YPYFPTKMSY 240
LQYETMYKDY CYVSRNYDED IEKILTLENL DTNDVVVEAP FTEVLQPQKT EEELRIQAEK 300
RKETGKRLQE QARLKRMEKL VQKQEEFEYF SKVRDQLIDE PKKKVLSVLQ NAGFDDERDF 360
KKYLHSLEQS LKKAQMVEAE DDSHLDEMNE DKTAQKFDLL DIADEDLNED QIKEKRKQRF 420
LKASQDARQK AKEEKERVAK EEEEKKLKEQ QWRETDLNGW IKDKRLKLNK LIKRRKEKLK 480
LRDEMKDRKS QVSQNRMKNL ASLAEDNVKQ GAKRNRHQAT IDNDPNDTFG ANDEDWLIYT 540
DITQNPEAFE EALEYEYKDI VELERLLLEH DPNFTEEDTL EAQYDWRNSI LHLFLRGPRP 600
HDSENIHEQH QMHLNVERIR VPEVIFQPTM GGQDQAGICE LSETILLKKF GSQPGKLSQT 660
SIDMVNNVLI TGGNAKVPGL KERIVKEFTG FLPTGTNITV NMSSDPSLDA WKGMAALARN 720
EEQYRKTVIS KKEYEEYGPE YIKEHKLGNT KYFED 755 
Gene Ontology
 GO:0031011; C:Ino80 complex; IDA:SGD.
 GO:0042766; P:nucleosome mobilization; IDA:SGD.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR004000; Actin-related. 
Pfam
 PF00022; Actin 
SMART
 SM00268; ACTIN 
PROSITE
  
PRINTS