CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035959
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Villin-like protein 
Protein Synonyms/Alias
  
Gene Name
 VILL 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
80QKLGGRDKSIHVKLDubiquitination[1]
478AVALQALKGSQDSSEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 574 AA 
Protein Sequence
MALGTSSPSP PAPPSSPQHI YTNTRTLGPP EPEGHAGGGY PTYTNVEVVN DGAESAAFKQ 60
LFRTWSEKRR RNQKLGGRDK SIHVKLDVGK LHTQPKLAAQ LRMVDDGSGK VEVWCIQDLH 120
RQPVDPKRHG QLCAGNCYLV LYTYQRLGRV QYILYLWQGH QATADEIEAL NSNAEELDVM 180
YGGVLVQEHV TMGSEPPHFL AIFQGQLVIF QERAGHHGKG QSASTTRLFQ VQGTDSHNTR 240
TMEVPARASS LNSSDIFLLV TASVCYLWFG KGCNGDQREM ARVVVTVISR KNEETVLEGQ 300
EPPHFWEALG GRAPYPSNKR LPEEVPSFQP RLFECSSHMG CLVLAEVGFF SQEDLDKYDI 360
MLLDTWQEIF LWLGEAASEW KEAVAWGQEY LKTHPAGRSP ATPIVLVKQG HEPPTFIGWF 420
FTWDPYKWTS HPSHKEVVDG SPAAASTISE ITAEVNNLRL SRWPGNGRAG AVALQALKGS 480
QDSSENDLVR SPKSAGSRTS SSVSSTSATI NGGLRREQLM HQAVEDLPEG VDPARREFYL 540
SDSDFQDIFG KSKEEFYSMA TWRQRQEKKQ LGFF 574 
Gene Ontology
 GO:0007010; P:cytoskeleton organization; IEA:InterPro. 
Interpro
 IPR007123; Gelsolin_dom.
 IPR015626; Villin-like.
 IPR007122; Villin/Gelsolin.
 IPR003128; Villin_headpiece. 
Pfam
 PF00626; Gelsolin
 PF02209; VHP 
SMART
 SM00262; GEL
 SM00153; VHP 
PROSITE
 PS51089; HP 
PRINTS
 PR00597; GELSOLIN.