CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039367
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Kinesin heavy chain isoform 5A 
Protein Synonyms/Alias
  
Gene Name
 Kif5a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
227TEQKLSGKLYLVDLAubiquitination[1]
241AGSEKVSKTGAEGAVubiquitination[1]
253GAVLDEAKNINKSLSubiquitination[1]
Reference
 [1] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Microtubule; Motor protein; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1027 AA 
Protein Sequence
MAETNNECSI KVLCRFRPLN QAEILRGDKF IPIFQGDDSV IIGGKPYVFD RVFPPNTTQE 60
QVYHACAMQI VKDVLAGYNG TIFAYGQTSS GKTHTMEGKL HDPQLMGIIP RIARDIFNHI 120
YSMDENLEFH IKVSYFEIYL DKIRDLLDVT KTNLSVHEDK NRVPFVKGCT ERFVSSPEEI 180
LDVIDEGKSN RHVAVTNMNE HSSRSHSIFL INIKQENIET EQKLSGKLYL VDLAGSEKVS 240
KTGAEGAVLD EAKNINKSLS ALGNVISALA EGTKSYVPYR DSKMTRILQD SLGGNCRTTM 300
FICCSPSSYN DAETKSTLMF GQRAKTIKNT ASVNLELTAE QWKKKYEKEK EKTKAQKETI 360
AKLEAELSRW RNGENVPETE RLAGEDSALA AEICEETPVN DNSSIVVRIA PEERQKYEEE 420
IRRLYKQLDD KDDEINQQSQ LIEKLKQQML DQEELLVSTR GDNEKVQREL SHLQSENDAA 480
KEEVKEVLQA LEELAVNYDQ KSQEVEEKSQ QNQLLVDELS QKVATMLSLE SELQRLQEVS 540
GHQRKRIAEV LNGLMKDLSE FSVIVGNGEI KLPVEISGAI EEEFTVARLY ISKIKSEVKS 600
VVKRCRQLEN LQVECHRKME VTGRELSSCQ LLISQHEAKI RSLTEYMQTV ELKKRHLEES 660
YDSLSDELAK LQAQETVHEV ALKDKEPDTQ DAEEVKKALE LQMENHREAH HRQLARLRDE 720
INEKQKTIDE LKDLNQKLQL ELEKLQADYE RLKNEENEKS AKLQELTFLY ERHEQSKQDL 780
KGLEETVARE LQTLHNLRKL FVQDVTTRVK KSAEMEPEDS GGIHSQKQKI SFLENNLEQL 840
TKVHKQLVRD NADLRCELPK LEKRLRATAE RVKALEGALK EAKEGAMKDK RRYQQEVDRI 900
KEAVRYKSSG KRGHSAQIAK PVRPGHYPAS SPTNPYGTRS PECISYTNNL FQNYQNLHLQ 960
AAPSSTSDVY FASNGATSVA PLASYQKANT DNGNATDIND NRSDLPCGYE AEDPAKLFPL 1020
HQETAAS 1027 
Gene Ontology
 GO:0035253; C:ciliary rootlet; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IEA:InterPro.
 GO:0043005; C:neuron projection; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0007018; P:microtubule-based movement; IEA:InterPro. 
Interpro
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00225; Kinesin 
SMART
 SM00129; KISc 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2 
PRINTS
 PR00380; KINESINHEAVY.