UniProt Accession

 HM20B_HUMAN; Q9P0W2; A6NMS5; D6W616; Q6IBP8; Q8NBD5; Q9HD21; Q9Y491; Q9Y4A2 

Genbank Protein ID

 AF146223; AL355709; AF331191; AF288679; AF072165; AK090733; AC005786; CH471139; CH471139; CH471139; BC002552; BC003505; BC004408; BC021585; AF072836; CR456754 

Genbank Nucleotide ID

 AAF66707.1; CAB90809.2; AAG60060.1; AAG01174.1; AAF76253.1; BAC03510.1; AAC62837.1; EAW69306.1; EAW69307.1; EAW69308.1; AAH02552.1; AAH03505.2; AAH04408.2; AAH21585.1; AAC26860.1; CAG33035.1 

Protein Name

 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related 

Protein Synonyms/Alias

 SMARCE1-related protein; BRCA2-associated factor 35; HMG box-containing protein 20B; HMG domain-containing protein 2; HMG domain-containing protein HMGX2; Sox-like transcriptional factor; Structural DNA-binding protein BRAF35 

Gene Name

 HMG20B 

Gene Synonyms/Alias

 BRAF35; HMGX2; HMGXB2; SMARCE1R 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
110	MLGAEWSKLQPTEKQ	ubiquitination	[1]
144	YQQSEAYKMCTEKIQ	ubiquitination	[1]
149	AYKMCTEKIQEKKIK	ubiquitination	[1]
208	AELRRLRKMNVAFEE	ubiquitination	[1]
300	RDPAQHEKLIVRIKE	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Required for correct progression through G2 phase of the cell cycle and entry into mitosis. Required for RCOR1/CoREST mediated repression of neuronal specific gene promoters. 

Sequence Annotation

 DNA_BIND 70 138 HMG box.  

Keyword

 Alternative splicing; Cell cycle; Chromatin regulator; Chromosome; Coiled coil; Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 317 AA 

Protein Sequence

Gene Ontology

 GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
 GO:0005654; C:nucleoplasm; TAS:Reactome.
 GO:0003677; F:DNA binding; NAS:UniProtKB.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.
 GO:0007596; P:blood coagulation; TAS:Reactome.
 GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
 GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
 GO:0006325; P:chromatin organization; NAS:UniProtKB.
 GO:0033234; P:negative regulation of protein sumoylation; IEA:Compara.
 GO:0045666; P:positive regulation of neuron differentiation; IEA:Compara.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR009071; HMG_box_dom. 

Pfam

 PF00505; HMG_box 

SMART

 SM00398; HMG 

PROSITE

 PS00353; HMG_BOX_1
 PS50118; HMG_BOX_2 

PRINTS