CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006095
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Vacuolar ATPase assembly integral membrane protein VPH2 
Protein Synonyms/Alias
 Protein VMA12 
Gene Name
 VPH2 
Gene Synonyms/Alias
 CLS10; VMA12; YKL119C; YKL520 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
54FYVKEYRKDSDLQCSubiquitination[1]
108LEYQSMVKRSKSVFSubiquitination[1]
111QSMVKRSKSVFSLQEubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Required for vacuolar ATPase assembly. 
Sequence Annotation
  
Keyword
 Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 215 AA 
Protein Sequence
MFEIKLNDRI TEFLRKFKNS AKSNEGIDED IDLFLKRHAI PMQSLLFYVK EYRKDSDLQC 60
SIKELLKPLE FEFKPKAVRG LHYSEDFKKK LEFLKYQEQE LEYQSMVKRS KSVFSLQEDD 120
ELTPSQINKQ IKEQVTTVFN VLVSVISVVV AIWYWTGSST NFPVHVRLLL CLFFGILVLV 180
ADVVVYNSYL KKLEEAKVKE KTKVEKKKVL SKITL 215 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0007035; P:vacuolar acidification; IMP:SGD.
 GO:0070072; P:vacuolar proton-transporting V-type ATPase complex assembly; IMP:SGD. 
Interpro
 IPR021013; ATPase_Vma12. 
Pfam
 PF11712; Vma12 
SMART
  
PROSITE
  
PRINTS