UniProt Accession

 IHFA_ECOLI; P0A6X7; P06984 

Genbank Protein ID

 K02844; V00291; U00096; AP009048; M14031 

Genbank Nucleotide ID

 AAA51471.1; CAA23566.1; AAC74782.1; BAA15480.1; AAA23525.1 

Protein Name

 Integration host factor subunit alpha 

Protein Synonyms/Alias

 IHF-alpha 

Gene Name

 ihfA 

Gene Synonyms/Alias

 hid; himA; b1712; JW1702 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
15	MSEYLFDKLGLSKRD	acetylation	[1]
20	FDKLGLSKRDAKELV	acetylation	[1]
24	GLSKRDAKELVELFF	acetylation	[1]
45	LENGEQVKLSGFGNF	acetylation	[1]
66	QRPGRNPKTGEDIPI	acetylation	[1]
86	VTFRPGQKLKSRVEN	acetylation	[1]
97	RVENASPKDE*****	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 One of the 2 subunits of integration host factor (IHF), a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. 

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; Conjugation; Cytoplasm; Direct protein sequencing; DNA recombination; DNA-binding; Reference proteome; Transcription; Transcription regulation; Translation regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 99 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:HAMAP.
 GO:0000746; P:conjugation; IEA:UniProtKB-KW.
 GO:0006310; P:DNA recombination; IEA:HAMAP.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:HAMAP.
 GO:0006417; P:regulation of translation; IEA:HAMAP.
 GO:0006351; P:transcription, DNA-dependent; IDA:EcoCyc. 

Interpro

 IPR023630; DNA-bd_HU/IHF.
 IPR000119; Hist_DNA-bd_bac.
 IPR020816; Histone-like_DNA-bd_CS.
 IPR010992; IHF-like_DNA-bd_dom.
 IPR005684; IHF_alpha. 

Pfam

 PF00216; Bac_DNA_binding 

SMART

 SM00411; BHL 

PROSITE

 PS00045; HISTONE_LIKE 

PRINTS

 PR01727; DNABINDINGHU.