CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043808
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Constitutive coactivator of PPAR-gamma-like protein 1 
Protein Synonyms/Alias
  
Gene Name
 FAM120A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
53LKLSRNGKSLTTSQYubiquitination[1]
147SDLDAIAKDVFQHSQubiquitination[1, 2, 3, 4]
327GNKIGWEKTGSHSEPubiquitination[4]
345GDPGDQTKAEGSSTAubiquitination[3, 5]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [5] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 494 AA 
Protein Sequence
XVAQSIEDHH QEVIGFCREN GFHGLVAYDS DYALCNIPYY FSAHALKLSR NGKSLTTSQY 60
LMHEVAKQLD LNPNRFPIFA ALLGNHILPD EDLASFHWSL LGPEHPLASL KVRAHQLVLP 120
PCDVVIKAVA DYVRNIQDTS DLDAIAKDVF QHSQSRTDDK VIRFKRAIGY YSATSKPMSF 180
HPPHYLAARP GPFGMPGMVP PHVPPQMLNI PQTSLQAKPV APQVPSPGGA PGQGPYPYSL 240
SEPAPLTLDT SGKNLTEQNS YSNIPHEGKH TPLYERSSPI NPAQSGSPNH VDSAYFPGSS 300
TSSSSDNDEG SGGATNHISG NKIGWEKTGS HSEPQARGDP GDQTKAEGSS TASSGSQLAE 360
GKGSQMGTVQ PIPCLLSMPT RNHMDITTPP LPPVAPEVLR VAEHRHKKGL MYPYIFHVLT 420
KGEIKIAVSI EDEANKDLPP AALLYRPVRQ YVYGVLFSLA ESRKKTERLA FRKNRLPPEC 480
MYCNNPLFVF LGTS 494 
Gene Ontology
  
Interpro
 IPR026783; Coact_PPARg-like_1. 
Pfam
  
SMART
  
PROSITE
  
PRINTS