CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002740
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Hemoglobin subunit theta-1 
Protein Synonyms/Alias
 Hemoglobin theta-1 chain; Theta-1-globin 
Gene Name
 HBQ1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
17LVRALWKKLGSNVGVubiquitination[1]
62QVRAHGQKVADALSLubiquitination[2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
  
Sequence Annotation
 METAL 59 59 Iron (heme distal ligand).
 METAL 88 88 Iron (heme proximal ligand).  
Keyword
 Complete proteome; Heme; Iron; Metal-binding; Oxygen transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 142 AA 
Protein Sequence
MALSAEDRAL VRALWKKLGS NVGVYTTEAL ERTFLAFPAT KTYFSHLDLS PGSSQVRAHG 60
QKVADALSLA VERLDDLPHA LSALSHLHAC QLRVDPASFQ LLGHCLLVTL ARHYPGDFSP 120
ALQASLDKFL SHVISALVSE YR 142 
Gene Ontology
 GO:0005833; C:hemoglobin complex; TAS:ProtInc.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0019825; F:oxygen binding; IEA:InterPro.
 GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW.
 GO:0015671; P:oxygen transport; TAS:ProtInc. 
Interpro
 IPR000971; Globin.
 IPR009050; Globin-like.
 IPR012292; Globin_dom.
 IPR002338; Haemoglobin_a.
 IPR002339; Haemoglobin_pi. 
Pfam
 PF00042; Globin 
SMART
  
PROSITE
 PS01033; GLOBIN 
PRINTS
 PR00612; ALPHAHAEM.
 PR00815; PIHAEM.