CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041714
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Alpha-internexin 
Protein Synonyms/Alias
 Internexin, alpha 
Gene Name
 Ina 
Gene Synonyms/Alias
 Inexa; rCG_57469 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
17CSASSYRKVFGDGSRacetylation[1]
88AARTNEYKIIRTNEKacetylation[1]
95KIIRTNEKEQLQGLNacetylation[1]
95KIIRTNEKEQLQGLNubiquitination[2]
216ARLDLEKKVESLLDEacetylation[1]
278QYESLAAKNLQSAEEubiquitination[2]
288QSAEEWYKSKFANLNacetylation[1]
290AEEWYKSKFANLNEQacetylation[1]
369ESDLRNTKSEMARHLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Intermediate filament; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 506 AA 
Protein Sequence
MSFGSEHYLC SASSYRKVFG DGSRLSARLS GPGGSGSFRS QSLSRSNVAS TAACSSASSL 60
GLGLAYRRLP ASDGLDLSQA AARTNEYKII RTNEKEQLQG LNDRFAVFIE KVHQLETQNR 120
ALEAELAALR QRHAEPSRVG ELFQRELREL RAQLEEASSA RAQALLERDG LAEEVQRLRA 180
RCEEESRGRE GAERALKAQQ RDVDGATLAR LDLEKKVESL LDELAFVRQV HDEEVAELLA 240
TLQASSQAAA EVDVAVAKPD LTSALREIRA QYESLAAKNL QSAEEWYKSK FANLNEQAAR 300
STEAIRASRE EIHEYRRQLQ ARTIEIEGLR GANESLERQI LELEERHSAE VAGYQDSIGQ 360
LESDLRNTKS EMARHLREYQ DLLNVKMALD IEIAAYRKLL EGEETRFSTS GLSISGLNPL 420
PNPSYLLPPR ILSSTTSKVS SAGLSLKKEE EEEEEEEEEG ASKEVTKKTS KVGESFEETL 480
EETVVSTKKT EKSTIEEITT SSNQKM 506 
Gene Ontology
 GO:0005883; C:neurofilament; IEA:Compara.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0060052; P:neurofilament cytoskeleton organization; IEA:Compara. 
Interpro
 IPR016044; F.
 IPR001664; IF.
 IPR006821; Intermed_filament_DNA-bd.
 IPR018039; Intermediate_filament_CS. 
Pfam
 PF00038; Filament
 PF04732; Filament_head 
SMART
  
PROSITE
 PS00226; IF 
PRINTS