CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034620
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein Tpx2 
Protein Synonyms/Alias
 TPX2, microtubule-associated protein homolog (Xenopus laevis) (Predicted), isoform CRA_a 
Gene Name
 Tpx2 
Gene Synonyms/Alias
 Tpx2_predicted; rCG_37362 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
128SVRLSAQKDLEQKEKacetylation[1]
373QTPILQTKYRARAVTacetylation[1]
387TCKSAAEKEAEELEKacetylation[1]
522PHYGVPYKPPIPETRacetylation[1]
580DTINLPEKKVKNATQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 744 AA 
Protein Sequence
MAQVPTAYSF DAPTDFINFS SLDAEEDTEN IDSWFDEKAN LENKFLRQSG IGEPFQGKTS 60
LRKAKLQQGC VTPLKAVDNT YYKETEKENL QKQSIPSNDC PSLNAKRAVT GTTPIQPQRR 120
SVRLSAQKDL EQKEKNHVAS VEMKAKRCTA PTTDYPPNKK MKVSHKKKPE EEEEGSAPAT 180
SRKDETLERA KGKHTVPAVP PAREKTVKST EEQELEKSLR MQQEVVEMRK KNEEFKKLAL 240
AGPGQPVKKS TSQVTKTVDF HFLTDERIKQ HPKSQEEYKE VNFMSELRKH SSTPARGTRG 300
CTIIKPFNLS KGKKRTFDEA ASTYVPIAQQ VEAFHKRTPN RYHLRNKKDE SLLPSKPVNK 360
IVRDPQTPIL QTKYRARAVT CKSAAEKEAE ELEKLQQYKF KARELDPRIF ESGPILPKRP 420
PVKPPTQPVG FDLEIEKRIH ERESKKKPED EQFEFHSRPC PTKILEDVVG VPEKKVIPAT 480
VPKSPVFALK NRIRVPVKED EEEEKPVVIK AQPVPHYGVP YKPPIPETRN VEVCPFSFDT 540
RDKERQLQKE KKIKEMQKGE VPKFKALPVP HFDTINLPEK KVKNATQAEP FSLETDKRGA 600
YKAEIWKHQL EEEQKQQKEA ACFKARPNTV IFQEPFVPKK EKKSAAENPS GSLVQEPFQL 660
ATEKRAKERQ ELEKKMAEME AWKLQQLAEV RQQEEEQQKE ELARLRKELV HKANPIRKYS 720
AVEVKSSELP LTVPVSPKFS TRFQ 744 
Gene Ontology
 GO:0005874; C:microtubule; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0000922; C:spindle pole; IEA:Compara.
 GO:0032147; P:activation of protein kinase activity; IEA:Compara.
 GO:0007067; P:mitosis; IEA:InterPro.
 GO:0060236; P:regulation of mitotic spindle organization; IEA:Compara. 
Interpro
 IPR015128; Aurora-A-bd.
 IPR027330; TPX2_central_dom.
 IPR027329; TPX2_dom_C.
 IPR009675; TPX2_fam. 
Pfam
 PF09041; Aurora-A_bind
 PF06886; TPX2
 PF12214; TPX2_importin 
SMART
  
PROSITE
  
PRINTS