UniProt Accession

 PGRC1_MOUSE; O55022; Q99JN0 

Genbank Protein ID

 AF042491; BC006016 

Genbank Nucleotide ID

 AAB97466.1; AAH06016.1 

Protein Name

 Membrane-associated progesterone receptor component 1 

Protein Synonyms/Alias

  

Gene Name

 Pgrmc1 

Gene Synonyms/Alias

 Pgrmc 

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
96	ILMAINGKVFDVTKG	ubiquitination	[1]
102	GKVFDVTKGRKFYGP	ubiquitination	[1]
105	FDVTKGRKFYGPEGP	acetylation	[2]
105	FDVTKGRKFYGPEGP	ubiquitination	[1]
132	LATFCLDKEALKDEY	ubiquitination	[1]
163	WDSQFTFKYHHVGKL	ubiquitination	[1]
169	FKYHHVGKLLKEGEE	ubiquitination	[1]
172	HHVGKLLKEGEEPTV	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 Receptor for progesterone (By similarity). 

Sequence Annotation

 DOMAIN 72 171 Cytochrome b5 heme-binding.
 MOD_RES 54 54 Phosphoserine (By similarity).
 MOD_RES 180 180 Phosphotyrosine.
 MOD_RES 181 181 Phosphoserine.  

Keyword

 Complete proteome; Direct protein sequencing; Endoplasmic reticulum; Lipid-binding; Membrane; Microsome; Phosphoprotein; Receptor; Reference proteome; Steroid-binding; Transmembrane; Transmembrane helix. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 195 AA 

Protein Sequence

Gene Ontology

 GO:0009986; C:cell surface; IEA:Compara.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
 GO:0007411; P:axon guidance; IEA:Compara. 

Interpro

 IPR001199; Cyt_B5-like_heme/steroid-bd. 

Pfam

 PF00173; Cyt-b5 

SMART

  

PROSITE

 PS00191; CYTOCHROME_B5_1
 PS50255; CYTOCHROME_B5_2 

PRINTS