CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035006
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein LOC100364956 
Protein Synonyms/Alias
  
Gene Name
 LOC683761 
Gene Synonyms/Alias
 LOC100364956 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
200RRYLEHGKETLLRSDacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Involved in the presentation of foreign antigens to the immune system (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Immunity; Membrane; MHC I; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 365 AA 
Protein Sequence
MGSRAPHTLL LLLAAALART QPRAGSHSLR YFTTALSRPG LGEPRFISVG YVDDTEFVRF 60
DSDAENPRYE PRAPWMEREG LEYWEQQTRR AKGNQQTFQV NLRTALHYYN QSEDRSHTIQ 120
RMYGCDVGSD GSLLRGYEQS AYDGRDYIAL NEDLKTWTAA DVAAQITRNK WDQAGVAERR 180
RAYLEGTCMK WLRRYLEHGK ETLLRSDPPK AHVTLHPRPE GDVTLRCWAL GFYPADITLT 240
WQLNGEDLTQ DMELVETRPA GDGTFQKWAS VVVPPGKEQN YTCRVEHEGL PEPLTLRWEA 300
PPSTDSNMET NVIYVVIGAI SAVAIIGAVL AVVRKKNTGG TGGDYTPAPG KANPNSSVSL 360
PDCKG 365 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0042612; C:MHC class I protein complex; IEA:UniProtKB-KW.
 GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; IEA:UniProtKB-KW.
 GO:0006955; P:immune response; IEA:InterPro. 
Interpro
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR003006; Ig/MHC_CS.
 IPR003597; Ig_C1-set.
 IPR011161; MHC_I-like_Ag-recog.
 IPR011162; MHC_I/II-like_Ag-recog.
 IPR001039; MHC_I_a_a1/a2.
 IPR010579; MHC_I_a_C. 
Pfam
 PF07654; C1-set
 PF00129; MHC_I
 PF06623; MHC_I_C 
SMART
 SM00407; IGc1 
PROSITE
 PS50835; IG_LIKE
 PS00290; IG_MHC 
PRINTS
 PR01638; MHCCLASSI.