CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039797
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Fermitin family homolog 3 
Protein Synonyms/Alias
  
Gene Name
 FERMT3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
5***MAGMKTASGDYIubiquitination[1]
155KEKKKKEKEPEEELYubiquitination[1]
166EELYDLSKVVLAGGVubiquitination[1]
222RPSSLSDKTQLHSRWubiquitination[1, 2, 3]
242CLMQQGIKAGDALWLubiquitination[1, 3]
252DALWLRFKYYSFFDLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 286 AA 
Protein Sequence
MAGMKTASGD YIDSSWELRV FVGEEDPEAE SVTLRVTGES HIGGVLLKIV EQINRKQDWS 60
DHAIWWEQKR QWLLQTHWTL DKYGILADAR LFFGPQHRPV ILRLPNRRAL RLRASFSQPL 120
FQAVAAICRL LSIRHPEELS LLRAPEKKEK KKKEKEPEEE LYDLSKVVLA GGVAPALFRG 180
MPAHFSDSAQ TEACYHMLSR PQPPPDPLLL QRLPRPSSLS DKTQLHSRWL DSSRCLMQQG 240
IKAGDALWLR FKYYSFFDLD PKTDPVRLTQ LYEQARWDLL LEEIDC 286 
Gene Ontology
 GO:0002102; C:podosome; IEA:Compara.
 GO:0033622; P:integrin activation; IEA:Compara.
 GO:0007159; P:leukocyte cell-cell adhesion; IEA:Compara.
 GO:0070527; P:platelet aggregation; IEA:Compara.
 GO:0033632; P:regulation of cell-cell adhesion mediated by integrin; IEA:Compara. 
Interpro
 IPR019748; FERM_central. 
Pfam
 PF00373; FERM_M 
SMART
  
PROSITE
  
PRINTS