CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034460
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Synaptojanin-1 
Protein Synonyms/Alias
  
Gene Name
 Synj1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
335TLKDLYGKQIVVNLLubiquitination[1]
454EALGLAEKPQLVTRFubiquitination[1]
532LNSDLADKARALLTTubiquitination[1]
558SASSKVLKNMCENFYubiquitination[1]
586TWNVNGGKQFRSIAFubiquitination[1]
617GIQEFQDKRSKPTDIubiquitination[1]
838EDYDTSEKCRTPAWTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1607 AA 
Protein Sequence
MRKSWTCWSG SDASGGCSGG GCGRRRRRSR RKRAASEERR MAFSKGFRIY HKLDPPPFSL 60
IVETRHKEEC LMFESGAVAV LSSAEKEAIK GTYAKVLDAY GLLGVLRLNL GDTMLHYLVL 120
VTGCMSVGKI QESEVFRVTS TEFISLRVDA SDEDRISEVR KVLNSGNFYF AWSASGVSLD 180
LSLNAHRSMQ EHTTDNRFFW NQSLHLHLKH YGVNCDDWLL RLMCGGVEIR TIYAAHKQAK 240
ACLISRLSCE RAGTRFNVRG TNDDGHVANF VETEQVIYLD DCVSSFIQIR GSVPLFWEQP 300
GLQVGSHRVR MSRGFEANAP AFDRHFRTLK DLYGKQIVVN LLGSKEGEHM LSKAFQSHLK 360
ASEHASDIHM VSFDYHQMVK GGKAEKLHSI LKPQVQKFLD YGFFYFDGSE VQRCQSGTVR 420
TNCLDCLDRT NSVQAFLGLE MLAKQLEALG LAEKPQLVTR FQEVFRSMWS VNGDSISKIY 480
AGTGALEGKA KLKDGARSVT RTIQNNFFDS SKQEAIDVLL LGNTLNSDLA DKARALLTTG 540
SLRVSEQTLQ SASSKVLKNM CENFYKYSKP KKIRVCVGTW NVNGGKQFRS IAFKNQTLTD 600
WLLDAPKLAG IQEFQDKRSK PTDIFAIGFE EMVELNAGNI VNASTTNQKL WAVELQKTIS 660
RDNKYVLLAS EQLVGVCLFV FIRPQHAPFI RDVAVDTVKT GMGGATGNKG AVAIRMLFHT 720
TSLCFVCSHF AAGQSQVKER NEDFVEIARK LSFPMGRMLF SHDYVFWCGD FNYRIDLPNE 780
EVKELIRQQN WDSLIAGDQL INQKNAGQIF RGFLEGKVTF APTYKYDLFS EDYDTSEKCR 840
TPAWTDRVLW RRRKWPFDRS AEDLDLLNAS FQDESKILYT WTPGTLLHYG RAELKTSDHR 900
PVVALIDIDI FEVEAEERQK IYKEVIAVQG PPDGTVLVSI KSSAQESTFF DDALIDELLR 960
QFAHFGEVIL IRFVEDKMWV TFLEGSSALN ALSLNGKELL NRTITITLKS PDWIKHLEEE 1020
MSLEKISVTL PSSASSTLLG EDAEVAADFD MEGDVDDYSA EVEELLPQHL QPSSSSGLGT 1080
SPSSSPRTSP CQSPTVPEYS APSLPIRPSR APSRTPGPPS SQGSPVDTQP AAQKDSSQTL 1140
EPKRPPPPRP VAPPARPAPP QRPPPPSGAR SPAPARKEFG GVGAPPSPGV ARREIEAPKS 1200
PGTARKDNIG RNQPSPQAGL AGPGPAGYGA ARPTIPARAG VISAPQSQAR VCAGRPTPDS 1260
QSKPSETLKG PAVLPEPLKP QAAFPQQPSL PTPAQKLQDP LVPIAAPTMP PSGPQPNLET 1320
PPQPPPRSRS SQSLPSDSSP QLQVKINGIS GVKQEPTLKS DPFEDLSLSV LAVSKAQPSV 1380
QISPVLTPDP KMLIQLPSAS QSQVNPLSSV SCMPTRPPGP EESKSQESMG SSANPFPSLP 1440
CRNPFTDRTA APGNPFRVQS QESEATSWLS KEEPVPNSPF PPLMPLSHDT SKASSSLGGF 1500
EDNFDLQSQS TVKTSNPKGW VTFDEDDNFP TTGKSKSVCP DLVGNAPASF DDDWSKGASV 1560
SFCVLPARRP PPPPPPVPLL PPGTTSSAGP STTLPSKAPS TLDFTER 1607 
Gene Ontology
 GO:0030118; C:clathrin coat; TAS:MGI.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0000166; F:nucleotide binding; IEA:InterPro.
 GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IMP:MGI.
 GO:0046855; P:inositol phosphate dephosphorylation; IMP:MGI.
 GO:0007612; P:learning; IMP:MGI.
 GO:0046856; P:phosphatidylinositol dephosphorylation; IMP:MGI.
 GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:MGI.
 GO:0016082; P:synaptic vesicle priming; IMP:MGI.
 GO:0016191; P:synaptic vesicle uncoating; IMP:MGI. 
Interpro
 IPR015047; DUF1866.
 IPR005135; Endo/exonuclease/phosphatase.
 IPR000300; IPPc.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom.
 IPR002013; Syja_N. 
Pfam
 PF08952; DUF1866
 PF03372; Exo_endo_phos
 PF02383; Syja_N 
SMART
 SM00128; IPPc 
PROSITE
 PS50102; RRM
 PS50275; SAC 
PRINTS