CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016670
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Phosphoglucomutase-like protein 5 
Protein Synonyms/Alias
  
Gene Name
 Pgm5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
354DRVAKSMKVPVYETPubiquitination[1]
441DYEGLEPKATYYIMRacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Component of adherens-type cell-cell and cell-matrix junctions. Lacks phosphoglucomutase activity (By similarity). 
Sequence Annotation
 METAL 293 293 Magnesium (Potential).
 METAL 295 295 Magnesium (Potential).
 METAL 297 297 Magnesium (Potential).
 MOD_RES 120 120 Phosphothreonine.
 MOD_RES 122 122 Phosphoserine.  
Keyword
 Carbohydrate metabolism; Cell adhesion; Cell junction; Complete proteome; Cytoplasm; Cytoskeleton; Glucose metabolism; Magnesium; Metal-binding; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 567 AA 
Protein Sequence
MEGSPIPVLT VPTAPYEDQR PTGGGGLRRP TGLFEGQRNY LPNFIQSVLS SIDLRDRQGC 60
TMVVGSDGRY FSRTATEIVV QMAAANGIGR LIIGQNGILS TPAVSCIIRK IKAAGGIILT 120
ASHCPGGPGG EFGVKFNVAN GGPAPDVVSD KIYQISKTIE EYAICPDLRI DLSRLGRQEF 180
DLENKFKPFR VEIVDPVDIY LNLLRNIFDF NAIKSLLTGP SQLKIRVDAM HGVMGPYVRK 240
VLCDELGAPA NSAINCVPLE DFGGQHPDPN LTYATTLLEA MKGGEYGFGA AFDADGDRYM 300
ILGQNGFFVS PSDSLAIIAA NLSCIPYFRQ MGVRGFGRSM PTSTALDRVA KSMKVPVYET 360
PAGWRFFSNL MDSGRCSLCG EESFGTGSDH LREKDGLWAV LVWLSIIAAR KQSVEEIVRD 420
HWAKYGRHYY CRFDYEGLEP KATYYIMRDL EALVTDKSFI GQQFAVGSHI YSIAKTDSFE 480
YVDPVDGTVT KKQGLRIIFS DASRLIFRLS SSSGVRATIR LYAESYERDP SGHDQEPQAV 540
LSPLIAIALK ISQIHERTGR RGPTVIT 567 
Gene Ontology
 GO:0043034; C:costamere; IBA:RefGenome.
 GO:0016010; C:dystrophin-associated glycoprotein complex; IDA:MGI.
 GO:0005925; C:focal adhesion; IBA:RefGenome.
 GO:0014704; C:intercalated disc; IBA:RefGenome.
 GO:0009898; C:internal side of plasma membrane; IBA:RefGenome.
 GO:0042383; C:sarcolemma; IBA:RefGenome.
 GO:0005914; C:spot adherens junction; IBA:RefGenome.
 GO:0001725; C:stress fiber; IBA:RefGenome.
 GO:0030018; C:Z disc; IDA:MGI.
 GO:0000287; F:magnesium ion binding; IEA:InterPro.
 GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
 GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW. 
Interpro
 IPR005844; A-D-PHexomutase_a/b/a-I.
 IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
 IPR005845; A-D-PHexomutase_a/b/a-II.
 IPR005846; A-D-PHexomutase_a/b/a-III.
 IPR016066; A-D-PHexomutase_CS.
 IPR005841; Alpha-D-phosphohexomutase_SF. 
Pfam
 PF02878; PGM_PMM_I
 PF02879; PGM_PMM_II
 PF02880; PGM_PMM_III 
SMART
  
PROSITE
 PS00710; PGM_PMM
 PS00134; TRYPSIN_HIS 
PRINTS
 PR00509; PGMPMM.