CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040861
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Probable ATP-dependent RNA helicase DDX31 
Protein Synonyms/Alias
  
Gene Name
 DDX31 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
152RSQTGSGKTLAYCIPubiquitination[1]
601ATYPRELKHIFHVRSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Helicase; Hydrolase; Nucleotide-binding; Reference proteome; RNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 722 AA 
Protein Sequence
MQAKATKRKY QASSEAPPAK RRNETSFLPA KKTSVKETQR TFKGNAQKMF SPKKHSVSTS 60
DRNQEERQCI KTSSLFKNNP DIPELHRPVV KQVQEKVFTS AAFHELGLHP HLISTINTVL 120
KMSSMTSVQK QSIPVLLEGR DALVRSQTGS GKTLAYCIPV VQSLQAMESK IQRSDGPYAL 180
VLVPTRELAL QSFDTVQKLL KPFTWIVPGV LMGGEKRKSE KARLRKGINI LISTPGRLVD 240
HIKSTKNIHF SRLRWLVFDE ADRILDLGFE KDITVILNAV NAECQKRQNV LLSATLTEGV 300
TRLADISLHD PVSISVLDKS HDQLNPKDKA VQEVCPPPAG DKLDSFAIPE SLKQHVTVVP 360
SKLRLVCLAA FILQKCKFEE DQKMVVFFSS CELVEFHYSL FLQTLLSSSG APASGQLPSA 420
SMRLKFLRLH GGMEQEERTA VFQEFSHSRR GVLLCTDVAA RGLDLPQVTW IVQYNAPSSP 480
AEYIHRIGRT ARIGCHGSSL LILAPSEAEY VNSLASHKIN VSEIKMEDIL CVLTRDDCFK 540
GKRWGAQKSH AVGPQEIRER ATVLQTVFED YVHSSERRVS WAKKALQSFI QAYATYPREL 600
KHIFHVRSLH LGHVAKSFGL RDAPRNLSAL TRKKRKAHVK RPDLHKKTQS KHSLAEILRS 660
EYSSGMEADI AKVKKQNAPG EPGGRPLQHS LQPTPCFGRG KTLKWRKTQK GVQRDSKTSQ 720
KV 722 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:UniProtKB-KW. 
Interpro
 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR025313; DUF4217.
 IPR014001; Helicase_ATP-bd.
 IPR001650; Helicase_C.
 IPR027417; P-loop_NTPase.
 IPR000629; RNA-helicase_DEAD-box_CS.
 IPR014014; RNA_helicase_DEAD_Q_motif. 
Pfam
 PF00270; DEAD
 PF13959; DUF4217
 PF00271; Helicase_C 
SMART
 SM00487; DEXDc
 SM00490; HELICc 
PROSITE
 PS00039; DEAD_ATP_HELICASE
 PS51192; HELICASE_ATP_BIND_1
 PS51194; HELICASE_CTER
 PS51195; Q_MOTIF 
PRINTS