CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043787
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Transmembrane protein 245 
Protein Synonyms/Alias
  
Gene Name
 TMEM245 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
134GREWITHKLHKILGDubiquitination[1]
142LHKILGDKVNNTAVIubiquitination[2]
151NNTAVIEKQVLELWDubiquitination[3]
468RDISEDLKSSVG***ubiquitination[4]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 472 AA 
Protein Sequence
XEKRYHVWWG IIESFLKERQ GALAPWPIVG LGKFLLKVDS KMIIWLEKML DKIISIFIIF 60
LLVIGTLLLA LLLTAKVHQE SVHMIEVTSN LINETLANHP EWANWLPEAQ VVQRALNSAA 120
NNVYQYGREW ITHKLHKILG DKVNNTAVIE KQVLELWDRL YHSWFVKNVT HSGRHKGQKL 180
HVSRQNSWLG DILDWQDIVS FVHENIETFL SILESLWIVM SRNVSLLFTT VTTLLTILFY 240
SGTALLNFVL SLIIFLTTLF YLLSSSDEYY KPVKWVISLT PLSQPGPSSN IIGQSVEEAI 300
RGVFDASLKM AGFYGLYTWL THTMFGINIV FIPSALAAIL GAVPFLGTYW AAVPAVLDLW 360
LTQGLGCKAI LLLIFHLLPT YFVDTAIYSD ISGGGHPYLT GLAVAGGAYY LGLEGAIIGP 420
ILLCILVVAS NIYSAMLVSP TNSVPTPNQT PWPAQPQRTF RDISEDLKSS VG 472 
Gene Ontology
  
Interpro
 IPR002549; UPF0118. 
Pfam
 PF01594; UPF0118 
SMART
  
PROSITE
  
PRINTS