CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020886
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Activating signal cointegrator 1 complex subunit 1 
Protein Synonyms/Alias
 ASC-1 complex subunit p50; Trip4 complex subunit p50 
Gene Name
 Ascc1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
302NLYTADGKYIFKEREubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Enhances NF-kappa-B, SRF and AP1 transactivation. 
Sequence Annotation
 DOMAIN 57 119 KH.  
Keyword
 Complete proteome; Cytoplasm; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 356 AA 
Protein Sequence
MDVLRPQIVT FDGRNYRKNP IQEKQYQHEE DEDFYPDSME YSDEPCGAYE VAQTPHGFRA 60
TVSAPSLLYK HIVGKRGDTK KKIEVETKTS INIPKHGHEG EIVITGQHRN GVVSARTRID 120
VLLDTFRRRQ PFTHFLSFFL NEVEVQERFL MFQEEVLRKC SKDRGVDSTI FQNPKKLHLT 180
IGMLVLLSEQ EIQQTCEILQ RCKEEFINDI SGGRPLEVEM AGIEYMNDDP AMVDVLYAKV 240
HMKDGSNRLQ ELVDRVLERF QSLGLIVKEW TSVKLHATVM NTLLRKDPNA EGRYNLYTAD 300
GKYIFKERES FDGRNILKTF ENFYFGSLRL NSIHISQRFT VDSFGNYASC GHVDFS 356 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0005667; C:transcription factor complex; IEA:Compara.
 GO:0003824; F:catalytic activity; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR009210; Euk_LigT.
 IPR004087; KH_dom.
 IPR004088; KH_dom_type_1.
 IPR019510; Kinase-A_anchor_nucl_local_sig.
 IPR009097; RNA_ligase/cNuc_Pdiesterase. 
Pfam
 PF10469; AKAP7_NLS
 PF00013; KH_1 
SMART
 SM00322; KH 
PROSITE
 PS50084; KH_TYPE_1 
PRINTS