CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030602
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 F-box only protein 18 
Protein Synonyms/Alias
 cDNA FLJ16282 fis, clone NT2RI3005416, highly similar to F-box only protein 18 (EC 3.6.1.-) 
Gene Name
 FBXO18 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
34NSVLAEGKGGFIRAKubiquitination[1]
98RLWDNMRKLGECTEEubiquitination[1]
264IHLIGGIKSFGLDRIubiquitination[1]
329AKIAVVEKYNIRIPEubiquitination[1]
380LGTVHKAKGLEFDTVubiquitination[1]
395HVLDDFVKVPCARHNubiquitination[1]
495PITYSNRKENKGGYLubiquitination[1]
498YSNRKENKGGYLCHSubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 547 AA 
Protein Sequence
MAYGHIGRKY QSKKKLNLFK LTPFMVNSVL AEGKGGFIRA KLVCKTLENF FASADEELTI 60
DHVPIWCKNS QGQRVMVEQS EKLNGVLEAS RLWDNMRKLG ECTEEAHQMT HDGYLKLWQL 120
SKPSLASFDA IFVDEAQDCT PAIMNIVLSQ PCGKIFVGDP HQQIYTFRGA VNALFTVPHT 180
HVFYLTQSFR FGVEIAYVGA TILDVCKRVR KKTLVGGNHQ SGIRGDAKGQ VALLSRTNAN 240
VFDEAVRVTE GEFPSRIHLI GGIKSFGLDR IIDIWILLQP EEERRKQNLV IKDKFIRRWV 300
HKEGFSGFKR YVTAAEDKEL EAKIAVVEKY NIRIPELVQR IEKCHIEDLD FAEMESHHVG 360
QAGLELPTSE YILGTVHKAK GLEFDTVHVL DDFVKVPCAR HNLPQLPHFR VESFSEDEWN 420
LLYVAVTRAK KRLIMTKSLE NILTLAGEYF LQAELTSNVL KTGVVRCCVG QCNNAIPVDT 480
VLTMKKLPIT YSNRKENKGG YLCHSCAEQR IGPLAFLTAS PEQVRAMERT VENIVLPRHE 540
ALLFLVF 547 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004003; F:ATP-dependent DNA helicase activity; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:InterPro. 
Interpro
 IPR014017; DNA_helicase_UvrD-like_C.
 IPR000212; DNA_helicase_UvrD/REP.
 IPR027417; P-loop_NTPase.
 IPR014016; UvrD-like_ATP-bd. 
Pfam
 PF00580; UvrD-helicase
 PF13361; UvrD_C 
SMART
  
PROSITE
  
PRINTS