UniProt Accession

 B8ZZK2_HUMAN; B8ZZK2 

Genbank Protein ID

 AC005154 

Genbank Nucleotide ID

  

Protein Name

 Gamma-glutamylcyclotransferase 

Protein Synonyms/Alias

  

Gene Name

 GGCT 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
118	KVATQEGKEITCRSY	ubiquitination	[1]
140	APPSPQYKKVEKETS	ubiquitination	[1, 2]
141	PPSPQYKKVEKETSH	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 166 AA 

Protein Sequence

Gene Ontology

 GO:0003839; F:gamma-glutamylcyclotransferase activity; IEA:InterPro.
 GO:0006750; P:glutathione biosynthetic process; IEA:InterPro. 

Interpro

 IPR013024; Butirosin_synth_BtrG-like.
 IPR017939; G-Glutamylcylcotransferase. 

Pfam

  

SMART

  

PROSITE

  

PRINTS