UniProt Accession

 I3L167_HUMAN; I3L167 

Genbank Protein ID

 AC012676; CH471112 

Genbank Nucleotide ID

 EAW85306.1 

Protein Name

 Coronin 

Protein Synonyms/Alias

  

Gene Name

 CORO7-PAM16 

Gene Synonyms/Alias

 hCG_2045878 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
103	GSADRTVKLWRLPGP	ubiquitination	[1]
157	VKVWDAAKQQPLTEL	ubiquitination	[1]
188	ALVGTACKDKQLRIF	ubiquitination	[1, 2, 3]
190	VGTACKDKQLRIFDP	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome; Repeat; WD repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 535 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; IEA:InterPro. 

Interpro

 IPR027331; CORO7.
 IPR015505; Coronin.
 IPR015049; DUF1900.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 

Pfam

 PF08954; DUF1900
 PF00400; WD40 

SMART

 SM00320; WD40 

PROSITE

 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 

PRINTS