CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003584
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Riboflavin biosynthesis protein RibF 
Protein Synonyms/Alias
 Riboflavin kinase; Flavokinase; FMN adenylyltransferase; FAD pyrophosphorylase; FAD synthase 
Gene Name
 ribF 
Gene Synonyms/Alias
 yaaC; b0025; JW0023 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
114FISDLLVKHLRVKFLacetylation[1]
119LVKHLRVKFLAVGDDacetylation[1]
235EVLGLGEKPLPGVANacetylation[1]
293FASLDELKAQIARDEacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; FAD; FMN; Kinase; Multifunctional enzyme; Nucleotide-binding; Nucleotidyltransferase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 313 AA 
Protein Sequence
MKLIRGIHNL SQAPQEGCVL TIGNFDGVHR GHRALLQGLQ EEGRKRNLPV MVMLFEPQPL 60
ELFATDKAPA RLTRLREKLR YLAECGVDYV LCVRFDRRFA ALTAQNFISD LLVKHLRVKF 120
LAVGDDFRFG AGREGDFLLL QKAGMEYGFD ITSTQTFCEG GVRISSTAVR QALADDNLAL 180
AESLLGHPFA ISGRVVHGDE LGRTIGFPTA NVPLRRQVSP VKGVYAVEVL GLGEKPLPGV 240
ANIGTRPTVA GIRQQLEVHL LDVAMDLYGR HIQVVLRKKI RNEQRFASLD ELKAQIARDE 300
LTAREFFGLT KPA 313 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003919; F:FMN adenylyltransferase activity; IGI:EcoCyc.
 GO:0008531; F:riboflavin kinase activity; IGI:EcoCyc.
 GO:0006747; P:FAD biosynthetic process; IEA:UniProtKB-UniPathway.
 GO:0009398; P:FMN biosynthetic process; IEA:UniProtKB-UniPathway.
 GO:0009231; P:riboflavin biosynthetic process; IEA:InterPro. 
Interpro
 IPR015864; FAD_synthase.
 IPR023468; Riboflavin_kinase.
 IPR002606; Riboflavin_kinase_bac.
 IPR015865; Riboflavin_kinase_bac/euk.
 IPR023465; Riboflavin_kinase_domain.
 IPR014729; Rossmann-like_a/b/a_fold. 
Pfam
 PF06574; FAD_syn
 PF01687; Flavokinase 
SMART
 SM00904; Flavokinase 
PROSITE
  
PRINTS