UniProt Accession

 TBCA_MOUSE; P48428 

Genbank Protein ID

 U05333; BC034267; BC051475; BC055749 

Genbank Nucleotide ID

 AAA83250.1; AAH34267.1; AAH51475.1; AAH55749.1 

Protein Name

 Tubulin-specific chaperone A 

Protein Synonyms/Alias

 TCP1-chaperonin cofactor A; Tubulin-folding cofactor A; CFA 

Gene Name

 Tbca 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
51	DGENYAIKKQAEILQ	acetylation	[1]
52	GENYAIKKQAEILQE	ubiquitination	[2]
95	LEEAEEYKEARVVLD	ubiquitination	[2]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Tubulin-folding protein; involved in the early step of the tubulin folding pathway. 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine (By similarity).  

Keyword

 Acetylation; Chaperone; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 108 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0007021; P:tubulin complex assembly; IEA:InterPro. 

Interpro

 IPR004226; CofA_tubulin-bd. 

Pfam

 PF02970; TBCA 

SMART

  

PROSITE

  

PRINTS