UniProt Accession

 F5GXW0_HUMAN; F5GXW0 

Genbank Protein ID

 AL139352; Z97053 

Genbank Nucleotide ID

  

Protein Name

 Adenosine deaminase 

Protein Synonyms/Alias

  

Gene Name

 ADA 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
171	KVVELCKKYQQQTVV	ubiquitination	[1]
225	VGSAEVVKEAVDILK	ubiquitination	[1, 2, 3]
232	KEAVDILKTERLGHG	acetylation	[3]
232	KEAVDILKTERLGHG	ubiquitination	[1, 2, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 263 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0005886; C:plasma membrane; IDA:HPA.
 GO:0019239; F:deaminase activity; IEA:InterPro.
 GO:0009168; P:purine ribonucleoside monophosphate biosynthetic process; IEA:InterPro. 

Interpro

 IPR001365; A/AMP_deaminase_dom.
 IPR006330; Ado/ade_deaminase. 

Pfam

 PF00962; A_deaminase 

SMART

  

PROSITE

  

PRINTS