| Tag | Content |
|---|
| CPLM ID | CPLM-011719 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphatidylinositol 4-kinase 2 |
Protein Synonyms/Alias | PI4-kinase 2; PtdIns-4-kinase 2; Phosphatidylinositol 4-OH kinase beta2; PI-4Kbeta2 |
Gene Name | PI4KBETA2 |
Gene Synonyms/Alias | At5g09350; T5E8.150 |
Created Date | July 27, 2013 |
Organism | Arabidopsis thaliana (Mouse-ear cress) |
NCBI Taxa ID | 3702 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 293 | NNSEGFFKRLRSSKG | acetylation | [1] |
|
Reference | [1] Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis. Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ. Plant Physiol. 2011 Apr;155(4):1779-90. [ PMID: 21311031] |
Functional Description | Acts on phosphatidylinositol (PtdIns) in the first committed step in the production of the second messenger inositol- 1,4,5-trisphosphate (By similarity). Necessary for proper organization of the trans-Golgi network (TGN) and post-Golgi secretion in root hairs. Together with PI4KBETA1, required during polarized root hair expansion and pollen tube elongation. |
Sequence Annotation | DOMAIN 1 143 PIK helical.
REPEAT 210 229 1.
REPEAT 242 261 2.
REPEAT 264 283 3.
REPEAT 286 304 4.
REPEAT 307 326 5.
REPEAT 329 348 6.
REPEAT 351 370 7.
REPEAT 378 396 8.
REPEAT 418 436 9.
REPEAT 452 470 10.
REPEAT 488 507 11.
DOMAIN 854 1116 PI3K/PI4K.
REGION 210 507 11 X 20 AA approximate repeats.
MOD_RES 447 447 Phosphoserine (By similarity).
MOD_RES 452 452 Phosphoserine (By similarity). |
Keyword | Complete proteome; Cytoplasmic vesicle; Developmental protein; Kinase; Membrane; Phosphoprotein; Reference proteome; Repeat; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1116 AA |
Protein Sequence | MQMAQFLSLV RGDSIESPRE ITSPSNLISE SGSNGWLIRF FDSSFFCEWI AVSYLYKHQH 60
SGVRDYLCNR MYTLPLSGIE SYLFQICYLM VHKPSPSLDK FVIDICAKSL KIALKVHWFL 120
LAELEDSDDN EGISRIQEKC QIAATLVGEW SPLMRPHNEP STPGSKVLNK FLSSKQKLFS 180
LTLSPPTQKS LLFSPTSGSN LQDDGSQLSA DDNKIFKRLI PSPKVRDALL FRKSADKEDE 240
ECEKDGFFKR LLRDSRGEDD EQRSNSEGFF KRLLKDNKSE EEEISNNSEG FFKRLRSSKG 300
DEEELTSSSD GFFKRLLRDN KGDEEELGAN SEGFFKKLLR DSKNEDEEPN ANTEGFFKKL 360
FHESKNEDDK VSNAVDDEEK DGFLKKLFKE KFDEKRNGNE RNETDETVYT DETSGEDNGR 420
EGFFKKLFKE KFEDKPNIGK ADDGNESEDD ESSEFSLFRR LFRRHPEDVK TTLPSENCSN 480
GGFVESSPGT ENFFRKLFRD RDRSVEDSEL FGSKKYKEKC PGSPKPQNNT PSKKPPLPNN 540
TAAQFRKGSY HESLEFVHAL CETSYDLVDI FPIEDRKTAL RESIAEINSH LAQAETTGGI 600
CFPMGRGVYR VVNIPEDEYV LLNSREKVPY MICVEVLKAE TPCGAKTTST SLKLSKGGIP 660
LANGDAFLHK PPPWAYPLST AQEVYRNSAD RMSLSTVEAI DQAMTHKSEV KLVNACLSVE 720
THSNSNTKSV SSGVTGVLRT GLESDLEWVR LVLTADPGLR MESITDPKTP RRKEHRRVSS 780
IVAYEEVRAA AAKGEAPPGL PLKGAGQDSS DAQPMANGGM LKAGDALSGE FWEGKRLRIR 840
KDSIYGNLPG WDLRSIIVKS GDDCRQEHLA VQLISHFFDI FQEAGLPLWL RPYEVLVTSS 900
YTALIETIPD TASIHSIKSR YPNITSLRDF FDAKFKENSP SFKLAQRNFV ESMAGYSLVC 960
YLLQIKDRHN GNLLMDEEGH IIHIDFGFML SNSPGGVNFE SAPFKLTREL LEVMDSDAEG 1020
LPSEFFDYFK VLCIQGFLTC RKHAERIILL VEMLQDSGFP CFKGGPRTIQ NLRKRFHLSL 1080
TEEQCVSLVL SLISSSLDAW RTRQYDYYQR VLNGIR 1116 |
Gene Ontology | GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB. GO:0004430; F:1-phosphatidylinositol 4-kinase activity; ISS:UniProtKB. GO:0006661; P:phosphatidylinositol biosynthetic process; IEA:InterPro. GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. GO:0009860; P:pollen tube growth; IGI:TAIR. GO:0048768; P:root hair cell tip growth; IGI:TAIR. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |