CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015665
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 534 
Protein Synonyms/Alias
 KRAB domain only protein 3 
Gene Name
 ZNF534 
Gene Synonyms/Alias
 KRBO3 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
277YNNKECGKVFSHHAYacetylation[1]
290AYLAQHRKIHTGEKPacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
 May be involved in transcriptional regulation (By similarity). 
Sequence Annotation
 DOMAIN 8 92 KRAB.
 ZN_FING 199 221 C2H2-type 1; degenerate.
 ZN_FING 227 249 C2H2-type 2.
 ZN_FING 255 277 C2H2-type 3; degenerate.
 ZN_FING 283 305 C2H2-type 4; degenerate.
 ZN_FING 311 333 C2H2-type 5.
 ZN_FING 339 361 C2H2-type 6.
 ZN_FING 367 389 C2H2-type 7.
 ZN_FING 395 417 C2H2-type 8.
 ZN_FING 423 445 C2H2-type 9.
 ZN_FING 451 473 C2H2-type 10.
 ZN_FING 479 501 C2H2-type 11.
 ZN_FING 507 529 C2H2-type 12.
 ZN_FING 535 557 C2H2-type 13.
 ZN_FING 563 585 C2H2-type 14.
 ZN_FING 591 613 C2H2-type 15.
 ZN_FING 619 641 C2H2-type 16.
 ZN_FING 647 669 C2H2-type 17.  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 674 AA 
Protein Sequence
MALTQGQLSF SDVAIEFSQE EWKCLDPGQK ALYRDVMLEN YRNLVSLGIC LPDLSVTSML 60
EQKRDPWTLQ SEVKIINNPD GRECIKGVNT EKSSKLGSSA GNKSLKNQHG LTLQLHLTEW 120
QPFQAVRNIY GCKHVEKSIS DNSSVSPVQI SFFSVKTHIF NNYRNDFLFS TLLPQEQKVH 180
IREKPYGCNE HGKVFRVSSS LTNRQVIHIA DKTYKCSDCG EIFSSNSNFA QHQRIHTGEK 240
PYKYNECGKV FNQNSHLAQH QKIHTGQKPY NNKECGKVFS HHAYLAQHRK IHTGEKPYKC 300
SECGKAFSVC SSLTAHLVIH TGEKPYDCKE CGKVFRHKSS LTTHQTVHTG ERPYKCNECG 360
KGFSRIAFLA RHRKVHTGEK PYKCNECGKV FIGNSRLARH RKIHTGGRRY KCNECGKAFR 420
TCSDLTAHLL IHTGEKPYEC IDCGKVFRHK SSLTYHCRIH TGEKPYKCNE CGKVFSQNSN 480
LQRHRKIHTG EKLYKCNECG KVFRQNSHLA QHRDIHTGEK PYSCNECGKV FRRNSHLVRH 540
RNVHTGEKPY SCNECGKVFS RNSHLARHRN IHTGEKPHSC NECGKVFSRN SHLARHRKIH 600
TGEKLYKCNE CSKVFSRNSR LAQHRNIHTG VKPYSCNECG KVFSKNSILV QHCSIHTREK 660
P 661 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS