UniProt Accession

 A4D275_HUMAN; A4D275 

Genbank Protein ID

 AK314818; CH236956; CH471091; CH471091; CH471091; CH471091 

Genbank Nucleotide ID

 BAG37341.1; EAL23882.1; EAW76677.1; EAW76678.1; EAW76679.1; EAW76680.1 

Protein Name

 Actin related protein 2/3 complex, subunit 1B, 41kDa 

Protein Synonyms/Alias

 Actin related protein 2/3 complex, subunit 1B, 41kDa, isoform CRA_a; cDNA, FLJ95695, Homo sapiens actin related protein 2/3 complex, subunit 1B, 41kDa(ARPC1B), mRNA 

Gene Name

 ARPC1B 

Gene Synonyms/Alias

 hCG_19475; tcag7.662 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
82	NAYVWTLKGRTWKPT	ubiquitination	[1]
110	RWAPNENKFAVGSGS	ubiquitination	[1]
289	GGRLDVPKQSSQRGL	ubiquitination	[2]
367	KSLESALKDLKIK**	ubiquitination	[2]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Repeat; WD repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 372 AA 

Protein Sequence

Gene Ontology

 GO:0005856; C:cytoskeleton; IEA:InterPro.
 GO:0030833; P:regulation of actin filament polymerization; IEA:InterPro. 

Interpro

 IPR017383; ARPC2/3_su1.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 

Pfam

 PF00400; WD40 

SMART

 SM00320; WD40 

PROSITE

 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 

PRINTS