CPLM 1.0 - Compendium of Protein Lysine Modification| Tag | Content |
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| CPLM ID | CPLM-001948 | UniProt Accession | | Genbank Protein ID | | Genbank Nucleotide ID | | Protein Name | Histone H3.3C | Protein Synonyms/Alias | Embryonic | Gene Name | H3f3c | Gene Synonyms/Alias | Gm14384 | Created Date | July 27, 2013 | Organism | Mus musculus (Mouse) | NCBI Taxa ID | 10090 | Lysine Modification | Position | Peptide | Type | References |
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| 57 | REIRRYQKSTELLIR | ubiquitination | [1] | | 80 | REIAQDFKTDLRFQS | ubiquitination | [1] |
| Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] | Functional Description | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Sequence Annotation | MOD_RES 4 4 Phosphothreonine; by GSG2 (By
MOD_RES 5 5 Allysine; alternate (By similarity).
MOD_RES 5 5 N6,N6,N6-trimethyllysine; alternate (By
MOD_RES 5 5 N6,N6-dimethyllysine; alternate (By
MOD_RES 5 5 N6-acetyllysine; alternate (By
MOD_RES 5 5 N6-methyllysine; alternate (By
MOD_RES 7 7 Phosphothreonine; by PKC (By similarity).
MOD_RES 9 9 Citrulline; alternate (By similarity).
MOD_RES 9 9 Symmetric dimethylarginine; by PRMT5;
MOD_RES 10 10 N6,N6,N6-trimethyllysine; alternate (By
MOD_RES 10 10 N6,N6-dimethyllysine; alternate (By
MOD_RES 10 10 N6-acetyllysine; alternate (By
MOD_RES 10 10 N6-methyllysine; alternate (By
MOD_RES 11 11 Phosphoserine; by AURKB, AURKC, RPS6KA3,
MOD_RES 12 12 Phosphothreonine; by PKC (By similarity).
MOD_RES 15 15 N6-acetyllysine (By similarity).
MOD_RES 18 18 Asymmetric dimethylarginine; by CARM1;
MOD_RES 18 18 Citrulline; alternate (By similarity).
MOD_RES 19 19 N6-acetyllysine; alternate (By
MOD_RES 19 19 N6-methyllysine; alternate (By
MOD_RES 24 24 N6-acetyllysine; alternate (By
MOD_RES 24 24 N6-methyllysine; alternate (By
MOD_RES 28 28 N6,N6,N6-trimethyllysine; alternate (By
MOD_RES 28 28 N6,N6-dimethyllysine; alternate (By
MOD_RES 28 28 N6-acetyllysine; alternate (By
MOD_RES 28 28 N6-methyllysine; alternate (By
MOD_RES 29 29 Phosphoserine; by AURKB, AURKC and
MOD_RES 32 32 Phosphoserine (By similarity).
MOD_RES 37 37 N6,N6,N6-trimethyllysine; alternate (By
MOD_RES 37 37 N6,N6-dimethyllysine; alternate (By
MOD_RES 37 37 N6-acetyllysine; alternate (By
MOD_RES 37 37 N6-methyllysine; alternate (By
MOD_RES 38 38 N6-methyllysine (By similarity).
MOD_RES 42 42 Phosphotyrosine (By similarity).
MOD_RES 57 57 N6,N6,N6-trimethyllysine; alternate (By
MOD_RES 57 57 N6-acetyllysine; alternate (By
MOD_RES 57 57 N6-methyllysine; by EHMT2; alternate (By
MOD_RES 58 58 Phosphoserine (By similarity).
MOD_RES 65 65 N6-methyllysine (By similarity).
MOD_RES 80 80 N6,N6,N6-trimethyllysine; alternate (By
MOD_RES 80 80 N6,N6-dimethyllysine; alternate (By
MOD_RES 80 80 N6-acetyllysine; alternate (By
MOD_RES 80 80 N6-methyllysine; alternate (By
MOD_RES 81 81 Phosphothreonine (By similarity).
MOD_RES 108 108 Phosphothreonine (By similarity).
MOD_RES 123 123 N6-methyllysine (By similarity). | Keyword | Acetylation; Chromosome; Citrullination; Complete proteome; DNA-binding; Methylation; Nucleosome core; Nucleus; Phosphoprotein; Reference proteome. | Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL | Protein Length | 136 AA | Protein Sequence | MALTKQTARK STGGKAPRKQ LATKATRKSA PSTGGVKKPH RYRPGTVALR EIRRYQKSTE 60
LLIRKLPFQR LVREIAQDFK TDLRFQSAAI GALQEASEAY LVGLFEDTNL CAIHAKRVTI 120
MPKDIQLARR IRGERA 136 | Gene Ontology | | Interpro | | Pfam | | SMART | | PROSITE | | PRINTS | |
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