UniProt Accession

 CDCA4_HUMAN; Q9BXL8; Q8TB18; Q9NWK7 

Genbank Protein ID

 AF322239; BC011736; BC025263; AK000771 

Genbank Nucleotide ID

 AAK31075.1; AAH11736.1; AAH25263.1; BAA91373.1 

Protein Name

 Cell division cycle-associated protein 4 

Protein Synonyms/Alias

 Hematopoietic progenitor protein 

Gene Name

 CDCA4 

Gene Synonyms/Alias

 HEPP 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
9	FARGLKRKCVGHEED	ubiquitination	[1]
25	EGALAGLKTVSSYSL	ubiquitination	[1]
160	ENRGSFHKSLDQIFE	ubiquitination	[1, 2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 May participate in the regulation of cell proliferation through the E2F/RB pathway. May be involved in molecular regulation of hematopoietic stem cells and progenitor cell lineage commitment and differentiation (By similarity). 

Sequence Annotation

 DOMAIN 30 77 SERTA.  

Keyword

 Complete proteome; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 241 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. 

Interpro

 IPR009263; SERTA. 

Pfam

 PF06031; SERTA 

SMART

  

PROSITE

 PS51053; SERTA 

PRINTS