Tag | Content |
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CPLM ID | CPLM-014762 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Elongation factor 1-delta |
Protein Synonyms/Alias | EF-1-delta |
Gene Name | Eef1d |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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17 | KIWFDKFKYDDAERR | acetylation | [1] | 107 | DLQQAISKLEVRLST | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Isoform 1: EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1- alpha for another round of transfer of aminoacyl-tRNAs to the ribosome (By similarity). |
Sequence Annotation | REGION 80 115 Leucine-zipper (By similarity). REGION 173 281 Catalytic (GEF) (By similarity). MOD_RES 2 2 N-acetylalanine (By similarity). MOD_RES 17 17 N6-acetyllysine (By similarity). MOD_RES 107 107 N6-acetyllysine (By similarity). MOD_RES 117 117 N6-acetyllysine (By similarity). MOD_RES 129 129 Phosphothreonine (By similarity). MOD_RES 133 133 Phosphoserine (By similarity). MOD_RES 147 147 Phosphothreonine (By similarity). MOD_RES 162 162 Phosphoserine; by CK2. |
Keyword | Acetylation; Alternative splicing; Complete proteome; DNA-binding; Elongation factor; Nucleus; Phosphoprotein; Protein biosynthesis; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 281 AA |
Protein Sequence | MATNFLMHEK IWFDKFKYDD AERRFYEQMN GPVTAGSRQE NGASVILRDI ARARENIQKS 60 LAGSSGPGAS SGPGGDHSDL IVRIASLEVE NQNLRGVVQD LQQAISKLEV RLSTLEKSSP 120 THRATAPQTQ HVSPMRQVEP PAKKGATPAE DDEDNDIDLF GSDEEEEDKE AARLREERLR 180 QYAEKKAKKP TLVAKSSILL DVKPWDDETD MAQLETCVRS IQLDGLVWGA SKLVPVGYGI 240 RKLQIQCVVE DDKVGTDLLE EEITKFEEHV QSVDIAAFNK I 281 |
Gene Ontology | GO:0005853; C:eukaryotic translation elongation factor 1 complex; IEA:InterPro. GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0004871; F:signal transducer activity; IEA:Compara. GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW. GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEA:Compara. GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |