UniProt Accession

 PITC1_MOUSE; Q8K4R4; A2A650; A2A651; Q3TBB3; Q3U5F5; Q8K4R5 

Genbank Protein ID

 AB077281; AB077282; AK153625; AK171340; AL596116; AL645687; AL645905; AL596116; AL645687; AL645905; AL596116; AL645687; AL645905; AL645687; AL596116; AL645905; AL645687; AL596116; AL645905; AL645687; AL596116; AL645905; AL645905; AL596116; AL645687; AL645905; AL596116; AL645687; AL645905; AL596116; AL645687; BC108351 

Genbank Nucleotide ID

 BAC02913.1; BAC02914.1; BAE32124.1; BAE42401.1; CAM20633.1; CAM20633.1; CAM20633.1; CAM20627.1; CAM20627.1; CAM20627.1; CAM20628.1; CAM20628.1; CAM20628.1; CAM25441.1; CAM25441.1; CAM25441.1; CAM25442.1; CAM25442.1; CAM25442.1; CAM25443.1; CAM25443.1; CAM25443.1; CAM17314.1; CAM17314.1; CAM17314.1; CAM17315.1; CAM17315.1; CAM17315.1; CAM17317.1; CAM17317.1; CAM17317.1; AAI08352.1 

Protein Name

 Cytoplasmic phosphatidylinositol transfer protein 1 

Protein Synonyms/Alias

 Mammalian rdgB homolog beta; M-rdgB beta; MrdgBbeta; mM-rdgBbeta; Retinal degeneration B homolog beta; RdgBbeta 

Gene Name

 Pitpnc1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
67	KRVYLNSKLPSWARA	ubiquitination	[1]
78	WARAVVPKIFYVTEK	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

 Phosphatidylinositol transfer proteins mediate the monomeric transport of lipids by shielding a lipid from the aqueous environment and binding the lipid in a hydrophobic cavity. Able to transfer phosphatidylinositol in vitro. Isoform 2 specifically binds to phosphatidylinositol but not to other phospholipids and may play a role in the phosphoinositide-mediated signaling in the neural development. 

Sequence Annotation

 MOD_RES 274 274 Phosphoserine.  

Keyword

 Alternative splicing; Complete proteome; Cytoplasm; Lipid transport; Lipid-binding; Nucleus; Phosphoprotein; Reference proteome; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 332 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; ISS:UniProtKB.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
 GO:0008526; F:phosphatidylinositol transporter activity; ISS:UniProtKB.
 GO:0007165; P:signal transduction; ISS:UniProtKB. 

Interpro

 IPR001666; PI_transfer.
 IPR023393; START-like_dom. 

Pfam

 PF02121; IP_trans 

SMART

  

PROSITE

  

PRINTS

 PR00391; PITRANSFER.