CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005943
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Voltage-gated potassium channel Kch 
Protein Synonyms/Alias
  
Gene Name
 kch 
Gene Synonyms/Alias
 b1250; JW1242 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
281NLPEDDIKQLEQRLGacetylation[1]
305SNDSSVLKKAGIDRCacetylation[1]
349VLAVSDSKNLNKIKMacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 K(+)-specific ion channel. May play a role in the defense against osmotic shock. 
Sequence Annotation
 DOMAIN 245 371 RCK N-terminal.
 MOTIF 185 190 Selectivity filter.  
Keyword
 3D-structure; Cell inner membrane; Cell membrane; Complete proteome; Ion channel; Ion transport; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 417 AA 
Protein Sequence
MSHWATFKQT ATNLWVTLRH DILALAVFLN GLLIFKTIYG MSVNLLDIFH IKAFSELDLS 60
LLANAPLFML GVFLVLNSIG LLFRAKLAWA ISIILLLIAL IYTLHFYPWL KFSIGFCIFT 120
LVFLLILRKD FSHSSAAAGT IFAFISFTTL LFYSTYGALY LSEGFNPRIE SLMTAFYFSI 180
ETMSTVGYGD IVPVSESARL FTISVIISGI TVFATSMTSI FGPLIRGGFN KLVKGNNHTM 240
HRKDHFIVCG HSILAINTIL QLNQRGQNVT VISNLPEDDI KQLEQRLGDN ADVIPGDSND 300
SSVLKKAGID RCRAILALSD NDADNAFVVL SAKDMSSDVK TVLAVSDSKN LNKIKMVHPD 360
IILSPQLFGS EILARVLNGE EINNDMLVSM LLNSGHGIFS DNDELETKAD SKESAQK 417 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0006813; P:potassium ion transport; IEA:InterPro. 
Interpro
 IPR013099; Ion_trans_2.
 IPR016040; NAD(P)-bd_dom.
 IPR003148; RCK_N. 
Pfam
 PF07885; Ion_trans_2
 PF02254; TrkA_N 
SMART
  
PROSITE
 PS51201; RCK_N 
PRINTS